Arizona Diamondbacks vs Minnesota Twins Picks and Predictions for Saturday, September 13, 2025
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Diamondbacks vs Twins Game Information
The Arizona Diamondbacks play the second game of a three-game series on the road Saturday versus the Minnesota Twins at Target Field with a 6:10 PM ET first pitch. Arizona is 73–74 (35–40 away) and Minnesota is 64–82 (35–36 home). The matchup features right-handers Ryne Nelson (7–3, 3.48 ERA, 1.05 WHIP) for Arizona and Joe Ryan (13–8, 3.32 ERA, 1.01 WHIP) for Minnesota. Get ready for the final month of the baseball season with our free MLB Picks.
Arizona Diamondbacks Preview
Arizona uses contact hitting, speed, and timely power to score its runs. Geraldo Perdomo has been the steadiest hitter at .284/.383/.449 with 153 hits and 93 RBI, while Corbin Carroll is batting .254 with a team high 30 homers and has stolen 26 bases. If Ketel Marte is available (currently day-to-day), his .281/.381/.511 slash line adds another high-quality at-bat for the D-Backs.
On the mound. Nelson has thrown 137.0 innings with only 36 walks and 15 home runs allowed, and has an impressive 1.05 WHIP. Arizona’s recent 2–3 stretch included a series win in San Francisco thanks to five to six strong innings from the starting rotation and just enough offense to outscore its opponent, which may be enough against the Twins.
Minnesota Twins Preview
Minnesota’s biggest advantage is on the mound with Ryan. The right-hander has 176 strikeouts in 157.0 innings with just 34 walks, and a 1.01 WHIP shows Ryan can limit runs better than any starter the Twins have. Minnesota must limit walks against a Diamondbacks lineup that uses contact and speed to manufacture runs.
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The batting order for Minnesota is led by Byron Buxton. Buxton sits at .275/.337/.568 with 31 homers and 22 steals. At times, Buxton has carried the entire team, but Trevor Larnach’s 119 hits and the on-base percentage of Ryan Jeffers (.353) have helped to get more looks at the plate from the middle of the order.
Prediction Arizona Diamondbacks vs Minnesota Twins
Minnesota’s Jo Ryan will be the difference. The right-hander’s strike-throwing and confidence at home, along with Buxton’s bat, will carry the Twins to a win. Nelson will keep the D-Backs close, but Minnesota’s Ryan and a slight home-field advantage will be enough for the Twins to win.
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- Minnesota Twins moneyline
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