Arizona Diamondbacks vs San Diego Padres Picks and Predictions for Saturday, September 26th, 2026
Arizona Diamondbacks vs San Diego Padres Game Information
The Arizona Diamondbacks remain on the road Saturday with an 8:40 PM matchup in Petco Park in San Diego against the San Diego Padres. Arizona is a handful of games above .500 coming into this matchup, competing for the final wild card spot. The San Diego Padres stay home Saturday, well above .500, having already punched their ticket into the playoffs. Stay in the news with our MLB Picks.
Arizona Diamondbacks Preview
Eduardo Rodriguez got the start for Arizona in their last outing, giving up 2 runs on 9 hits across 6 innings to secure the victory. The Arizona bullpen faltered a bit, giving up 6 runs on 8 hits over the final 3 innings, but still did the job to secure the win. Gabriel Moreno and Nolan Arenado did the job in their last outing for Arizona, driving in 3 runs apiece to lead the way.
San Diego Padres Preview
Nick Pivetta got the star for San Diego last time out, allowing no runs on 4 hits across 4.2 innings. The San Diego bullpen was shaky, giving up 2 runs on 3 hits over the final 4.1 innings, but did the work to secure the win. San Diego had a balanced scoring attack in its last outing, with 4 different players driving in 1 run each.
Arizona Diamondbacks vs San Diego Padres Pitching Matchup
Corbin Burnes is listed to start Saturday for Arizona. Burnes has worked only 10⅓ innings since returning and owns a 7.84 ERA in that small sample. San Diego has not yet announced its probable starter, leaving the Padres' side of the pitching matchup uncertain. Burnes' track record is considerably stronger than his current ERA suggests, but his limited workload and difficult results since returning create legitimate questions.
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Arizona Diamondbacks vs San Diego Padres Pick
San Diego has the tentative advantage because of its stronger overall record and home-field advantage at Petco Park. Burnes can completely change the outlook if he returns to his established form, but his early results since returning have been shaky. Arizona will need him to settle in quickly against a Padres lineup capable of capitalizing on mistakes. Until San Diego announces its starter, this isn't a matchup to attack aggressively, but the Padres have enough advantages elsewhere to receive the initial nod.
- Pick: San Diego Padres
- Secondary: Pending San Diego Starter
- Lean: San Diego Padres Team Total Over
Final Score Prediction: San Diego Padres win 5-4
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