Arizona Diamondbacks vs San Diego Padres Picks and Predictions for Sunday, September 27th, 2026

By: Cameron Ross Published 09/27/2026, 03:10 AM ET

Arizona Diamondbacks vs San Diego Padres Game Information

The Arizona Diamondbacks will continue a late-season National League West series Sunday night at Petco Park against the San Diego Padres. Arizona enters the matchup at 84-74 and sits third in the NL West. San Diego is 88-70 and has secured its third consecutive postseason appearance. For more MLB action, see our MLB Picks.

Arizona Diamondbacks Preview

Arizona enters Saturday with a .246 team batting average, scoring 717 runs on 1315 hits. The Diamondbacks have posted a .317 OBP and a .402 team slugging percentage while hitting 162 home runs. Arizona has put together a solid offensive season, combining consistent hitting with enough extra-base power to generate more than 700 runs. Gabriel Moreno leads Arizona with a .311 batting average. Nolan Arenado is batting .254 and leads the team with 30 home runs and 85 RBIs.

San Diego Padres Preview

San Diego comes into this matchup with a .243 team batting average, producing 699 runs on 1280 hits. The Padres have a .318 OBP and a .397 slugging percentage with 180 home runs. Fernando TatisΒ leads San Diego with a .291 batting average this year. Mainly Machado is a .215 batting average leads the team with 29 home runs and 87 RBIs.

Arizona Diamondbacks vs San Diego Padres Pitching Matchup

Mike Soroka will take the mound for Arizona on Saturday. This season, Soroka is 9-5 with a 3.31 ERA across 111.1 innings. San Diego has yet to name a starter for Sunday and could rely heavily on their bullpen in this matchup.

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Arizona Diamondbacks vs San Diego Padres Pick

These teams are fairly close statistically, with Arizona owning the better batting average and San Diego holding the power advantage. The Padres have been the stronger team in the standings and will benefit from playing at Petco Park. Arizona should keep this matchup competitive, but San Diego's home-run power gives the Padres an opportunity to create separation with one or two swings.

  • Pick: San Diego Padres
  • Secondary: Over
  • Lean: San Diego Padres Team Total Over

Final Score Prediction: San Diego Padres win 5-4

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