Arizona Diamondbacks vs San Diego Padres Picks and Predictions for Sunday, September 28, 2025

By: Cameron Ross Published 09/28/2025, 01:00 AM ET
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Diamondbacks vs Padres Game Information

The Arizona Diamondbacks will be on the road Sunday for a game in Petco Park at 3:10 PM against the San Diego Padres to close the season. Arizona has been mediocre this season, hovering around .500 overall, coming into the final game of the season. The San Diego Padres are still on their home field in the season, as they have already clinched a playoff berth and will be preparing for October. Stay in the news with our MLB Picks.

Diamondbacks Preview

Offensively, Arizona has been mediocre this season. The Diamondbacks have a .251 batting average and have scored 782 runs on 1353 hits this season. The Diamondbacksโ€™ pitching has struggled all season, combining for a 4.43 team ERA. Geraldo Perdomo does most of the heavy lifting for Arizona, leading the team with a .291 batting average and 98 RBIs on the year. Corbin Carroll has supplied the most power for Arizona this year with 31 home runs to lead the team.

Padres Preview

The San Diego Padres are coming to the final day of the year as they playoff team heading into October. Offensively, San Diego has a .252 batting average this season, having scored 678 runs on 1339 hits. The San Diego pitching has been one of the team's biggest streaks this season, with a 3.64 team ERA. Manny Machado has anchored the San Diego offense this season, leading the team with 26 home runs and 93 RBI's. Luis Arraez is the top bat in the San Diego lineup with a .288 batting average.

Diamondbacks vs Padres Pitching Matchup

Brandon Pfaadt will take the mound Sunday for the final game of the season for the Arizona Diamondbacks. This season, Pfaadt is 13-8. This season, with a 5.00 ERA across 172.2 innings of work, the San Diego Padres have yet to name a starter for Sunday. San Diego could rely heavily on their bullpen as they rest their main arms on the final day of the year, as they have already clinched a playoff berth.

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Diamondbacks vs Padres Pick

The Arizona Diamondbacks will get the win on the final day of the year as they still compete for a playoff spot. Look for Arizona to throw the kitchen sink at San Diego in this matchup, leading to a road win. San Diego will rest a ton of their starters in this matchup as they prepare for a playoff run.

Pick: Arizona Diamondbacksย 

Secondary: ย Over

Lean: Corbin Carroll Over 1.5 Bases

Final Score Prediction: Arizona Diamondbacks win 7-4.

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