Arizona Diamondbacks vs Seattle Mariners Picks and Prediction for Friday May 29 2026

By: Kim Smith Published 05/29/2026, 12:40 AM ET
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The Arizona Diamondbacks and Seattle Mariners meet on Friday, May 29, 2026, at T-Mobile Park in Seattle, Washington. First pitch is scheduled for 10:10 PM ET with coverage available on MLB.TV. Seattle enters the matchup as the favorite according to the matchup predictor, and the game features two teams arriving with winning streaks after strong recent stretches. The available betting market information remains limited outside of matchup data. At the time of this writing the odds were not released. Be sure to check out our free MLB picks for more action around the league.

Starting Pitchers

Arizona is expected to start Zac Gallen, who enters this matchup with a 3-4 record, a 4.80 ERA, and a 1.44 WHIP across 54.1 innings. Gallen has allowed 61 hits while striking out 40 batters and walking 17 this season. Seattle is scheduled to counter with George Kirby, who comes into the game with a 5-4 record, a 3.54 ERA, and a 1.21 WHIP over 68.2 innings. Kirby has surrendered 67 hits while recording 55 strikeouts and 16 walks.

Diamondbacks Bringing Winning Streak Into Seattle

Arizona enters this matchup with a 31-24 overall record and a 13-14 road mark. The Diamondbacks are currently riding a five-game winning streak after recently sweeping both San Francisco and Colorado. During that stretch, Arizona scored at least five runs in four of the five victories, including a dominant 9-1 win over Colorado. The Diamondbacks have steadily climbed above .500 by playing consistent baseball on both sides of the field over the last two series.

Arizona is batting .248 as a team while scoring 255 runs and collecting 453 hits this season. The Diamondbacks have hit 48 home runs with a .314 on-base percentage and a .402 slugging percentage. Their pitching staff owns a 4.02 ERA with a 1.24 WHIP while opponents are batting .238 against them. Arizona has also recorded 392 strikeouts and holds a strong 17-13 record in night games this season.

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One of Arizonaโ€™s biggest strengths has been offensive consistency during the current winning streak. The Diamondbacks have produced six, seven, three, nine, and five runs over the last five games while continuing to limit opponents effectively with solid pitching numbers overall. That balanced production has helped Arizona stay competitive in nearly every recent matchup.

Mariners Looking to Continue Recent Surge at Home

Seattle enters Friday night with a 28-29 overall record and a 14-15 mark at home. The Mariners have also won three straight games after sweeping the Athletics on the road. Seattle scored 22 combined runs during the series, including two separate nine-run performances. Before the winning streak, the Mariners dropped back-to-back games against Kansas City but responded with one of their strongest offensive stretches in recent weeks.

The Mariners are batting .230 as a team while scoring 240 runs with 435 hits this season. Seattle has produced 66 home runs with a .317 on-base percentage and a .383 slugging percentage. On the mound, the Mariners own a 3.54 ERA with a 1.22 WHIP while opponents are batting .247 against them. Seattle has also recorded 485 strikeouts, which is one of the stronger totals in this matchup, while compiling a 15-20 record in night games.

The biggest strength for Seattle has been pitching. The Mariners hold the lower ERA in this matchup and have generated 485 strikeouts this season. Combined with the stronger starting pitching numbers entering this game, Seattle has the ability to slow down even productive offenses when the pitching staff is performing well.

Arizona Diamondbacks vs Seattle Mariners Picks and Prediction

Arizona Diamondbacks vs Seattle Mariners Pick

  • Pick: Seattle Mariners Moneyline

Seattle enters this game with the advantage on the mound and slightly stronger pitching numbers overall. The Mariners also come into the matchup with momentum after sweeping the Athletics and scoring 22 runs during the three-game stretch. Arizona has been excellent recently as well, but Seattleโ€™s lower ERA, strong strikeout numbers, and home-field advantage make the Mariners the more appealing side in this matchup. I think Seattleโ€™s pitching staff helps the Mariners edge out a close game.

Arizona Diamondbacks vs Seattle Mariners Total Pick

  • Pick: Under 7.5

Iโ€™m leaning toward the under because both teams enter this matchup with quality recent pitching performances and reliable starting pitchers on the mound. Seattle owns a 3.54 team ERA while Arizona has held opponents to a .238 batting average this season. Even though both offenses have been productive recently, this feels like a more controlled matchup compared to several of the other games on Fridayโ€™s schedule. With two teams capable of limiting mistakes on the mound, I think this game stays below the total.

Final Score Prediction: Seattle Mariners 4 โ€“ Arizona Diamondbacks 3

This prediction was written before the completion of game play on Thursday.

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