Athletics vs Boston Red Sox Picks and Predictions for Tuesday, September 16, 2025
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The Athletics visit Fenway Park on Tuesday at 6:45 p.m. ET to face the Boston Red Sox, with coverage on MLB.TV. Boston is favored on the moneyline, listed at -1.5 on the run line, and the total is set at 9 runs. Oakland enters at 70–80 overall, while Boston is 82–68 with a strong 45–30 home record. The Athletics are on the verge of being eliminated from postseason contention, while Boston is currently holding the second of three wildcard spots. Make your most informed bet with our free MLB Picks.
Athletics Preview
Oakland has won three straight and four of its last five, but lost two out of three last week to Boston. The lineup includes Nick Kurtz (32 home runs, .298 avg) and Jacob Wilson (.318 avg), while Tyler Soderstrom has chipped in with 24 homers and 88 RBI. Jeffrey Springs is expected to start, bringing a 10–11 record, 4.28 ERA, and 132 strikeouts in 162 innings. His home run issue (28 allowed) will be a test in Fenway’s hitter-friendly setting.
The A’s have received extra support from Shea Langeliers (30 home runs, .847 OPS) and Brent Rooker, who leads the team with 158 hits. Even without Max Muncy and Denzel Clarke in the lineup, Oakland has scored 21 runs across its last three games. If Springs and the bullpen can limit Boston’s hitting, Oakland has the bats to keep pace.
Red Sox Preview
Boston comes off a series split with the Yankees, capped by a 6–4 win on Sunday. Trevor Story leads the offense with 24 homers and 91 RBI, while Jarren Duran leads in hits with 148, a .333 on-base percentage, and 23 steals. Alex Bregman (.278 avg, .835 OPS) and Wilyer Abreu (22 home runs, .811 OPS) have been strong pieces, though Abreu is on the injured list.
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Boston has not announced its starting pitcher for this game. The Red Sox staff holds a 3.74 ERA, a clear edge over Oakland’s 4.77. Boston also shines in day games (36–23), and Fenway’s short porch helps a lineup that already makes strong contact. If they pressure Springs early, the Red Sox can control the game.
Athletics vs Red Sox Prediction
Boston has much better stats both at the plate and on the mound. The Red Sox are battling for both the American League East title and/or an AL wildcard. The Athletics are on the verge of being eliminated from playoff contention and have little more than pride to play for. Final Score Prediction: Boston Red Sox win 5-2.
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Best Bets
- Boston Red Sox -1.5
- Under Athletics Team Total 4
