Athletics vs Cincinnati Reds Picks, Prediction, Odds, and Line Movement for Wednesday August 5 2026

By: Kyle Kargel Published 08/05/2026, 08:28 AM ET
Athletics vs Reds picks

The Athletics and Cincinnati Reds run it back on Wednesday, August 5, with first pitch at 6:40 p.m. ET from Great American Ball Park. Cincinnati sits as a home favorite after taking the series opener, and bettors searching for more MLB predictions will want to see how the run line and total have shifted heading into Game 2, especially with two shaky rotations on the mound.

TLDR: Quick Picks and Prediction

  • Spread: Reds -1.5 (+139)
  • Total: Over 9.5
  • Moneyline lean: Cincinnati -151
  • Projected Final Score: Reds 8, Athletics 5

Odds and Line Movement

Cincinnati opened as a favorite and has only gotten shorter as the game approaches, a sign of confidence in a Reds club riding a four-of-five stretch. The total has been more volatile, swinging between 9.5 and 10 across multiple updates, which lines up with two bullpens and rotations that have struggled to limit baserunners all year.

Current Odds

Date Time Athletics Cincinnati Total Public ($, #)
08/05 04:29:21AM +114 -137 9Β½o-115 / 9Β½u-105 CIN 67%, 74%

Line Movement - Moneyline

Date Time Athletics Cincinnati Public ($, #)
08/05 04:29:21AM +114 -137 CIN 67%, 74%
08/05 01:46:27AM +114 -137 CIN 63%, 75%
08/05 01:46:27AM +114 -137 CIN 64%, 73%
08/04 09:27:55PM +118 -142 CIN 94%, 67%
08/04 06:45:13PM +118 -142 β€”
08/04 06:45:13PM +124 -150 β€”
08/04 04:39:34PM +129 -156 β€”
08/04 04:39:34PM +129 -156 β€”
08/04 04:11:39PM β€” β€” β€”
08/04 04:09:51PM +125 -151 β€”

Line Movement - Total

Date Time Over Under Public ($, #)
08/05 04:29:21AM 9Β½o-115 9Β½u-105 U75%, U67%
08/05 01:46:27AM 9Β½o-116 9Β½u-104 U81%, U67%
08/04 09:27:55PM 10o-102 10u-118 U94%, U88%
08/04 09:15:02PM 10o-103 10u-117 β€”
08/04 12:32PM 10o-102 10u-118 β€”
08/04 09:10:42PM 9Β½o-118 9Β½u-102 β€”
08/04 09:00:33PM 10o-102 10u-118 β€”
08/04 08:58:13PM 9Β½o-118 9Β½u-102 β€”
08/04 08:55:33PM 10o-102 10u-118 β€”
08/04 06:45:13PM 9Β½o-118 9Β½u-102 β€”
08/04 05:15:13PM 10o-103 10u-117 β€”
08/04 04:39:34PM 9Β½o-120 9Β½u+100 β€”
08/04 04:11:39PM β€” β€” β€”

Athletics vs Reds: Key Matchups and Game Preview

Cincinnati enters Wednesday having won four of its last five games and coming off a 5-4 victory in the series opener, while the Athletics have dropped six straight and continue looking for consistency.

Jacob Lopez on the Mound for the Athletics

Athletics left-hander Jacob Lopez is 5-4 with a 5.79 ERA and 1.67 WHIP across 70.0 innings this season, allowing 75 hits while striking out 61 and walking 42. Baserunners have been a persistent problem, and that trend does not figure to change in one of baseball's more hitter-friendly parks.

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Rhett Lowder Takes the Ball for Cincinnati

Cincinnati counters with right-hander Rhett Lowder, who is 3-7 with a 5.42 ERA and 1.52 WHIP over 83.0 innings, recording 70 strikeouts against 37 walks. Like Lopez, Lowder has struggled to consistently limit traffic on the bases, which sets up a game with plenty of scoring potential.

Athletics Offense Has Been Productive

Despite the losing streak, the Athletics have actually been the more productive offense overall, batting .245 with a .320 on-base percentage, a .400 slugging percentage, 491 runs and 134 home runs. Shea Langeliers has paced the club with 23 home runs, and Nick Kurtz has driven in 69 runs, though both Langeliers and Kurtz are now on the injured list.

Cincinnati Relies on Power and De La Cruz

Cincinnati is hitting .230 with a .310 OBP, a .397 slugging percentage, 467 runs and 145 home runs, leaning more heavily on power than average. Rookie Sal Stewart has emerged as the club's biggest run producer with 24 home runs and 86 RBIs, while Elly De La Cruz continues to set the tone atop the lineup with a .276 average, a .356 OBP and a .499 slugging percentage.

  • Cincinnati has won four of its last five games and took the series opener 5-4.
  • The Athletics have lost six straight games entering Wednesday.
  • Public money has consistently backed Cincinnati on the moneyline, reaching as high as 94% of dollars wagered.
  • The total has drawn heavy public support on the under at multiple price points, even as the number has moved between 9.5 and 10.
  • Team pitching favors Cincinnati, which owns a 4.40 ERA and 1.41 WHIP compared to the Athletics' 5.42 ERA and 1.50 WHIP.

Key Injuries and Things to Know: ATH vs CIN

  • The Athletics are without Nick Kurtz, one of their top run producers, along with starting pitcher Jeffrey Springs and center fielder Denzel Clarke.
  • Cincinnati is missing starter Nick Lodolo, reliever Tony Santillan and first baseman Spencer Steer.
  • Despite those absences, the Reds have continued to play well and carry momentum into Wednesday's matchup.
  • Both starting pitchers own ERAs above 5.40, and both bullpens have been inconsistent, adding risk to the later innings on either side.

Athletics vs Reds Side and Over/Under Picks

  • Spread Pick: Reds -1.5 (+139)
  • Total Pick: Over 9.5
  • Moneyline Lean: Cincinnati -151

The best betting value on the board is Cincinnati on the run line at -1.5, while the over 9.5 also deserves strong consideration given both starting pitchers carry ERAs above 5.40 and each bullpen has been inconsistent throughout the season.

Final Score Prediction: Reds vs Athletics

  • Cincinnati 8, Athletics 5
  • Winning Side: Reds -1.5
  • Total: Over 9.5

How to Wager on Reds vs Athletics

Bettors building out this card have a couple of strong angles to consider. Cincinnati -1.5 at +139 offers plus-money value on a team with momentum and a clear pitching edge, while the over 9.5 pairs naturally given both rotations' struggles to limit baserunners. For bettors who want an extra layer of analysis before placing a wager on this game or any other MLB matchup, it is worth checking out AI picks for model-driven projections, along with the Dimers review and the Oddible review for additional data-backed perspectives on tonight's Reds vs Athletics matchup.

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