Athletics vs Cleveland Guardians Picks and Prediction for Saturday September 19 2026

By: Eddie Kline Published 09/19/2026, 12:55 AM ET

Athletics Preview

Progressive Field will play host to a Saturday evening MLB clash between the Athletics and the Cleveland Guardians. Be ready for the baseball season with all of our MLB predictions. The Athletics (61-93) are looking to snap a four-game losing streak and will miss the playoffs for a sixth consecutive season. Last night, OF Zack Gelofโ€™s three-run blast in the opening frame was all the offense the Athletics could muster during a 5-3 road loss against Cleveland.ย 

Twenty-eight year old southpaw Jacob Lopez (6-4 5.02 ERA) will take the ball for the Athletics in this contest. Control has been an issue for Lopez, who has walked 56 batters and surrendered 20 long balls across 114 plus frames.ย 

Guardians Preview

The Cleveland Guardians have won three straight games and have edged a half-game ahead of Chicago for AL Central Division supremacy. During Fridayโ€™s home victory, Cleveland finally took the lead in the fifth inning on rookie 2B Travis Bazzanaโ€™s 15th home run. Veteran 3B Jose Ramirez went 2-for-5 with a home run and two RBIs. Closer Cade Smith notched his 38th save for the Guardians (79-75), who improved to 39-40 at home.ย 

Cleveland skipper Stephen Vogt will give the nod to twenty-seven year old righty Tanner Bibee (6-15 4.16 ERA) on Saturday. In his last start, Bibee (6.2 IP) allowed two runs and struck out seven batters during a 9-2 road triumph against Minnesota.ย 

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Athletics vs Guardians Pick

Cleveland 1B Rhys Hoskins (back) has started to swing a bat and hopes to return to the lineup before the end of the season. Through 154 games, the Athletics rank 15th in OPS and 21st in runs scored. For the season, Cleveland ranks 29th in OPS and 27th in runs scored. Take the over. Final Score Prediction, Cleveland Guardians win 7-4.ย 

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