Athletics vs Pittsburgh Pirates Picks and Prediction for Sunday September 21 2025
Athletics Preview
Scenic PNC Park will play host to a Sunday afternoon MLB clash between the Athletics and the Pittsburgh Pirates. Be ready for the baseball season with all of our MLB predictions. The Athletics have split their 80 road games and have been eliminated from postseason contention. Last night, the Athletics were limited to one hit and struck out 13 times during a 2-0 road loss against Pittsburgh.
Thirty-two year old southpaw Jeffrey Springs (10-11 4.17 ERA) will head to the hill for the Athletics in this contest. Through 166 innings of work, Springs has surrendered 28 long balls and ranks 21st in the majors with a 1.22 WHIP.
Pirates Preview
The Pittsburgh Pirates have dropped nine of their previous 11 games and are trapped in the NL Central Division cellar. During Saturday’s home victory, Nick Yorke and Bryan Reynolds delivered solo shots to provide the Pittsburgh offense. SP Bubba Chandler fired five shutout frames to earn the win for the Pirates (66-89), who improved to 43-37 at home.
Rookie right-hander Mike Burrows (2-4 4.10 ERA) will make his 19th career major league start for the Pirates. Last time out, Burrows (4.1 IP) gave up three runs and fanned six batters during a 4-3 road loss against Washington.
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Athletics vs Pirates Pick
Athletics OF Denzel Clarke (hip) experienced a setback while running the bases and will likely be shut down for the remainder of the season. Through 155 games, the Athletics rank 7th in OPS and 12th in runs scored. For the season, Pittsburgh ranks 30th in OPS and 30th in runs scored. Take the over. Final Score Prediction, Athletics win 6-5.
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