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Athletics vs St. Louis Cardinals Picks and Predictions, for Monday, September 1, 2025

By: David Anicetti Updated 09/01/2025, 01:31 PM ET

The Athletics open a three-game series on the road Monday versus the St Louis Cardinals. The Athletics dropped to 63-74 following Saturday’s 9-3 loss to the Texas Rangers. The A’s have lost each of the first two games of a three-game series versus Texas that concluded on Sunday. The Athletics trail first place in the American League West by 12.5 games and are 9.5 games behind the third and final AL wild card spot. Be ready for all the MLB action with our free MLB picks.

Jacob Wilson is batting .310 with an on-base percentage of .351 to lead the Athletics in both categories. Shea Langeliers leads in home runs with 29, while Brent Rooker leads in RBI with 78 and hits with 145. The A’s are batting .253 with a .432 slugging percentage. The Athletics have not announced their starting pitcher for the opening game of a three-game series on the road Monday versus St Louis.

The St Louis Cardinals improved to 68-69 following Saturday’s 4-2 victory over the Cincinnati Reds. Willson Contreras and Pedro Pages each hit a home run for the Cardinals. St Louis has won three straight but trails the first-place Milwaukee Brewers in the National League Central by 17 games, and the Cardinals are 5.5 games behind the third and final NL wild card spot.

Alec Burleson is batting .286 with 123 hits to lead St Louis in both categories. Willson Contreras leads in home runs with 20 and RBI was 74, while Brendan Donovan leads in on-base percentage at .348. St Louis is batting .247 with a .384 slugging percentage. On Monday, St Louis will send Sonny Gray to the mound. The right-hander is 12-7 with a 4.19 ERA, 168 Ks, and 28 BBs.

  • The Athletics are 6-4 in their last 10
  • The OVER has cashed in 4 of the A’s last 6
  • St Louis is 4-2 in its last 6
  • The UNDER has cashed in 3 of the Cardinals’ last 4

Cardinals vs A's Prediction

The St Louis Cardinals will open this series on Monday at home with the victory over the Athletics. St. Louis has won four of its last six, and the Cardinals are still in the hunt for a National League wild card, trailing the final spot by 5.5 games, while the Athletics are well off the pace of playoff contention, giving the Cards much more incentive to win. St Louis starter Sonny Gray has had two consecutive solid outings, allowing four runs across 12.0 innings. Final Score Prediction: St. Louis Cardinals win 6-2.

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