Baltimore Orioles vs San Diego Padres Picks and Prediction for Tuesday September 2 2025

By: Thomas Pemberton Updated 09/01/2025, 07:03 PM ET

The San Diego Padres continue their home series on Tuesday with the Baltimore Orioles in town. San Diego sits two games behind the LA Dodgers who lead the division. The Padres are 5-5 over their last ten games and carry a winning home field record. San Diego is averaging 4.2 runs scored per game. Stay up to date with our expert's MLB Picks.

San Diego Padres Preview

Yu Darvish will make his 11th start on the mound for the San Diego Padres. Darvish is 3-4 on the season with 47.2 innings pitched. Darvish has 42 strikeouts, 15 walks, and carries a 5.66 ERA. The San Diego Padres are allowing 7.3 hits per game which leads the MLB.

Baltimore Orioles Preview

The Baltimore Orioles have had their struggles all season. The Orioles have won two of their last ten games and sit last in the AL East. Baltimore is averaging 8.1 hits per game with 4.3 runs. The Orioles carry a losing road record into this series.

Tyler Wells will make his season debut for the Baltimore Orioles on Tuesday. Wells has been rehabbing an elbow injury all season. Well pitched 6.1 innings in his last appearance with Norfolk in Triple-A.

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Orioles vs Padres Pick & Prediction

The Baltimore Orioles carry a 4.73 team ERA. Yu Darvish has been up and down on the mound for San Diego most of the season. Darvish should find some success against a struggling Baltimore team. Tyler Wells makes his debut against a tough Padres team. Watch for this game to be one sided but the value is in the total. Final Score Prediction, San Diego Padres win 4-2 but the play is on the UNDER.

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