Best MLB Home Run Props for Wednesday, September 17, 2025

By: Devin Erickson-Sheehy Updated 09/17/2025, 11:28 AM ET
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We've got a loaded Wednesday MLB slate with all 30 teams in action and MLB picks for every game.

Here are the three best home run props today, targeting power bats in strong matchups. Bettors looking for value in the MLB prop bets can lock in these HR props backed by stats, recent form, and matchup data.

Top MLB HR Props Today

  • Kyle Schwarber +290

  • Rafael Devers +450

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  • Francisco Lindor  +520

Home Run Prop #1: Kyle Schwarber to Find the Seats

When it comes to MLB home run props, Kyle Schwarber remains one of the most bankable names on the board. Schwarber has crushed 53 long balls this season and has gone deep three times in his last eight games, showing no signs of slowing down as the Phillies push for postseason positioning.

Tonight he faces Blake Snell, a lefty-on-lefty matchup that might look tricky at first glance. But Schwarber has surprisingly thrived in these situations, belting 22 of his home runs this year against southpaws.

His elite barrel rate and top-tier hard-hit numbers make him a constant threat to leave the yard. Add in a shaky Dodgers bullpen behind Snell, and Schwarber offers one of the best home run props today at +290.

Also see: Phillies vs Dodgers pick

Home Run Prop #2: Rafael Devers to go Yard

Next up in our HR props list is Rafael Devers, who owns 31 home runs on the year despite battling through a minor cold stretch at the plate. Devers has a chance to break out tonight against the Arizona Diamondbacks, a team with one of the league’s worst bullpens and a starter in Brandon Pfaadt who has been prone to giving up the long ball.

Devers’ elite power plays in any ballpark, and the Giants’ third baseman consistently produces quality contact even during slumps.

At nearly 5-to-1 odds, Devers provides serious betting value and ranks as one of the most enticing MLB home run props on the board.

Also see: Giants vs Diamondbacks pick

Home Run Prop #3: Francisco Lindor with Sneaky Value

Finally, Francisco Lindor rounds out today’s trio of MLB prop bets with his +520  price tag. Lindor has been scorching hot in September, posting a .325 average and a .533 slugging percentage over his last 30 games. He homered just last night with a 381-foot blast at 104 mph exit velocity, a clear sign that his swing is locked in.

With 27 homers already this year and a strong history of driving the ball with authority, Lindor gets another favorable opportunity against the Padres’ pitching staff. Given his recent surge and ability to generate extra-base power from the shortstop position, Lindor is one of the most underrated home run prop bets for today.

Also see: Padres vs Mets pick

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