Boston Red Sox vs Baltimore Orioles Picks and Predictions for Friday April 24 2026
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The Boston Red Sox visit the Baltimore Orioles at Oriole Park at Camden Yards in Baltimore, Maryland, on Friday, April 24, 2026, with first pitch scheduled for 7:05 PM and coverage available on MLB.TV. The latest odds list Baltimore at -122 on the moneyline, while Boston is +102, with the total set at 8.5 runs and the Red Sox listed at -1.5 on the run line at +154 while the Orioles are +1.5 at -187. This American League matchup brings together a Boston team trying to steady itself and a Baltimore team looking to build on a recent road win, and readers should also check out free MLB picks for more baseball selections.
Starting Pitchers Set the Tone in Baltimore
Boston is expected to start Brayan Bello, who enters with a 1-2 record, a 6.75 ERA, and a 1.93 WHIP over 18.2 innings. He has allowed 24 hits, struck out 13, walked 12, and given up three home runs. Baltimore counters with Dean Kremer, who comes in at 0-1 with a 4.09 ERA and a 0.91 WHIP across 11.0 innings. Kremer has allowed 8 hits, recorded 16 strikeouts, issued 2 walks, and surrendered 4 home runs.
Boston Looks to Shake Off a Rough Stretch
The Red Sox enter this game with a 9-16 overall record and a 4-8 road mark. Boston has recently lost to New York three times and also recently lost to Detroit, though the Red Sox did pick up one recent win over Detroit during that five-game stretch. The recent results show a team that has had trouble stacking positive outcomes together.
Boston is batting .226 as a team with 90 runs scored, 180 hits, and 13 home runs. The Red Sox have a .310 on-base percentage and a .333 slugging percentage. On the pitching side, Boston owns a 4.39 ERA and a 1.32 WHIP, with 188 strikeouts, 87 walks, and a .242 opponent batting average.
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The biggest weakness for Boston is the combination of limited power and higher run prevention numbers. With only 13 home runs and a 4.39 team ERA, the Red Sox need cleaner pitching and more consistent offensive pressure to keep pace in this matchup.
Baltimore Returns Home With a Chance to Build
The Orioles come into Friday with a 12-13 overall record and a 6-6 record at home. Baltimore recently won over Kansas City twice, including one game that went 12 innings, but also recently lost to Kansas City and dropped two games to Cleveland. That gives the Orioles a mixed five-game stretch, though they enter this matchup having shown some fight offensively.
Baltimore is hitting .230 with 111 runs scored, 191 hits, and 26 home runs. The Orioles carry a .320 on-base percentage and a .381 slugging percentage. Their pitching staff has a 4.00 ERA and a 1.36 WHIP, with 221 strikeouts, 88 walks, and a .251 opponent batting average.
Baltimore’s key strength is its ability to generate offense through power and run production. The Orioles have scored 111 runs and hit 26 home runs, both of which stand out compared with Boston’s totals entering this matchup.
Boston Red Sox vs Baltimore Orioles Picks and Prediction
Boston Red Sox vs Baltimore Orioles Pick
Pick: Baltimore Orioles Moneyline
Baltimore is the pick on the moneyline because the Orioles have the stronger overall offensive profile in the provided numbers and enter with a slight edge at home. Baltimore has scored 111 runs compared with Boston’s 90 and has doubled Boston’s home run total, 26 to 13. The starting pitching matchup also favors Baltimore based on WHIP, with Kremer entering at 0.91 compared with Bello’s 1.93. With Boston coming off several recent losses and Baltimore showing more run production, the Orioles are the better side.
Boston Red Sox vs Baltimore Orioles Total Pick
Pick: Over 8.5
I would take the over 8.5 in this matchup because both teams have pitching numbers that leave room for scoring. Boston enters with a 4.39 team ERA, while Baltimore sits at 4.00, and both staffs have WHIP marks above 1.30 overall. The Red Sox starter has allowed 24 hits and 12 walks in 18.2 innings, while Baltimore’s offense has already produced 111 runs and 26 home runs. With those numbers, I expect enough offense to push this game over the total.
Final Score Prediction: Baltimore Orioles 6 – Boston Red Sox 4
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