Boston Red Sox vs Baltimore Orioles Picks and Predictions for Saturday April 25 2026

By: Kim Smith Published 04/25/2026, 12:35 AM ET
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The Boston Red Sox travel to face the Baltimore Orioles at Oriole Park at Camden Yards in Baltimore, Maryland on Saturday, April 25, 2026, with first pitch scheduled for 4:05 PM and coverage available on MLB.TV. At the time of this writing the odds were not released. This matchup features two teams trying to build momentum, with Baltimore holding a slight edge based on recent performance. If you’re looking for more angles on today’s games, you can browse free MLB picks.

Starting Pitchers Outlook

Boston is expected to start Garrett Crochet, while Baltimore counters with Trevor Rogers. Crochet enters with a 2-3 record, carrying a 7.88 ERA and a 1.63 WHIP across 24.0 innings. He has allowed 30 hits while striking out 30 batters and issuing nine walks, along with surrendering five home runs. On the other side, Rogers comes in with a 2-2 record and a 4.08 ERA, along with a 1.33 WHIP over 28.2 innings. He has given up 30 hits, struck out 25, walked eight, and allowed three home runs, showing more stability overall compared to his counterpart.

Boston’s Road Struggles Continue

Boston enters this contest with a 9-16 overall record and a 4-8 mark on the road. Their recent stretch has been difficult, as they recently lost three straight games to New York and also recently lost to Detroit, with their only recent win coming in a higher-scoring game against Detroit. That pattern reflects a team that has struggled to find consistent success, particularly against stronger opponents.

Looking at the numbers, the Red Sox are hitting .223 with 92 runs and 184 hits, along with 14 home runs. Their on-base percentage sits at .305, paired with a .331 slugging percentage. On the mound, they carry a 4.37 ERA with a 1.33 WHIP, allowing opponents to hit .243 while recording 205 strikeouts and issuing 89 walks.

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The key concern for Boston is its lack of offensive production. With a lower batting average and limited power output, the team has struggled to consistently generate runs, which has made it difficult to overcome pitching issues.

Baltimore Aiming to Stay Competitive at Home

Baltimore comes into this matchup with a 12-13 overall record and a balanced 6-6 record at home. Their recent form has been mixed, as they recently won over Kansas City twice but also recently lost to Kansas City and Cleveland. This inconsistency has kept them hovering around the .500 mark.

Statistically, the Orioles hold a .230 batting average with 111 runs and 191 hits, along with 26 home runs. Their .320 on-base percentage and .381 slugging percentage suggest a lineup capable of producing runs at a steady pace. On the pitching side, they carry a 4.00 ERA with a 1.36 WHIP, allowing opponents to hit .251 while striking out 221 batters and walking 88.

Baltimore’s biggest strength is its ability to generate power. With 26 home runs and a higher slugging percentage than Boston, they have shown they can create scoring opportunities quickly, which could play a major role in this game.

Red Sox vs Orioles Picks and Prediction

Red Sox vs Orioles Pick

Pick: Orioles Moneyline

Baltimore holds the edge in this matchup due to a more balanced offensive profile and a steadier performance on the mound. Trevor Rogers has been more effective than Garrett Crochet, particularly in limiting damage and maintaining a lower ERA and WHIP. Meanwhile, Boston’s struggles at the plate, combined with recent losses, suggest they may have difficulty keeping up if Baltimore generates early offense. With a stronger slugging percentage and more home run production, the Orioles appear to be in a better position to control this game.

Red Sox vs Orioles Total Pick

Pick: Over 8.5

I’m leaning toward the over in this matchup because Boston’s pitching struggles, particularly Crochet’s elevated ERA, could lead to scoring opportunities for Baltimore. At the same time, Baltimore’s pitching numbers suggest they can allow runs as well, especially with a WHIP over 1.30. With both teams showing the potential for offensive production in the right situations, this game has the feel of one that could push past the total.

Final Score Prediction: Baltimore Orioles 6 – Boston Red Sox 4

This prediction was written before the completion of game play on Friday.

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