Chicago Cubs vs Baltimore Orioles Picks and Prediction for Wednesday July 8 2026

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In Wednesday night MLB interleague action, the Chicago Cubs and the Baltimore Orioles will wrap up their series from Camden Yards. Be ready for the baseball season with all of our MLB predictions. The Cubs (51-40) have won eight of their last 11 games and trail NL Central Division leading Milwaukee by 6.5 games. Last night, C Miguel Amaya reached base three times and scored three runs out of the nine hole to spark Chicago to a 5-2 road victory. 

Thirty-six year old righty Colin Rea (6-5 4.74 ERA) will take the mound for the Cubs in this matchup. In his last start, Rea (5 IP) allowed two runs and retired five batters by strikes during a 23-3 home victory versus San Diego. 

Orioles Preview

The Baltimore Orioles have dropped seven of their previous 11 games and have fallen into the AL East Division basement. During Tuesday’s home loss, Baltimore batters went 1-for-9 with runners in scoring position and left seven men on base. C Adley Rutschman went 2-for-4 with a pair of RBIs for the Orioles (42-50), who fell to 24-24 at home. 

Baltimore manager Craig Albernaz will turn to thirty year old right-hander Dean Kremer (1-1 3.18 ERA) on Wednesday. Last time out, Kremer (6 IP) allowed four hits and one run during a 6-1 home victory versus Chicago. 

Cubs vs Orioles Pick

Chicago OF Matt Shaw (hand) will not play in this series and will not be activated until after the All-Star Break. Through 91 games, Chicago ranks 5th in OPS and 4th in runs scored. For the season, Baltimore ranks 17th in OPS and 13th in runs scored. Take the Orioles to win at home. Final Score Prediction, Baltimore Orioles win 6-3. 

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