Chicago Cubs vs Cincinnati Reds Picks and Prediction for Friday September 19 2025
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The Cincinnati Reds will look to keep their faint postseason chances alive when they host the Chicago Cubs on Friday night. Be ready for the baseball season with all of our MLB predictions.
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Game Details For Reds vs Cubs
- September 19th, 2025
- 6:40 pm EST
- The Great American Ball Park
- TV MARQ
Cubs Spotlight Player
- Thirty-two year old southpaw Shota Imanaga (9-7 3.29 ERA) has put together consecutive solid campaigns for the Cubs. In his lone start versus Cincinnati this season, Imanaga (6.1 IP) allowed three hits and one run while retiring seven batters by strikes.
Cubs Supporting Cast & Depth
- Switch-hitting OF Ian Happ has been on a tear for the Cubs. Over the last four games, Happ is 5-for-14 with two home runs and five RBIs. Happ has seven hits in 20 career at-bats versus Cincinnati SP Nick Lodolo.
- Chicago’s bullpen currently ranks fifth in the National League with a 3.75 ERA and has notched 42 saves.
Reds Spotlight Player
- Cincinnati 1B Spencer Steer ranks second on the club with 18 home runs. During Wednesday’s victory at St. Louis, Steer went 3-for-4 with a long ball and five RBIs. Chicago SP Shota Imanaga has surrendered eight home runs over his last 31 innings.
Reds Supporting Cast & Depth
- Cincinnati skipper Terry Francona will turn to talented left-hander Nick Lodolo (8-8 3.30 ERA) on Friday. In three appearances this season versus Chicago, Lodolo has fanned 12 batters across 12 plus frames.
- Cincinnati’s bullpen ranks in the middle of the pack with a 4.09 ERA and has converted just 35 of 57 save opportunities.
Betting Line Breakdown
- CIN -144, CHC +122, Total N/A
- Shota Imanaga has lasted at least six innings in seven of his previous eight starts. He will pitch deep enough into this game to earn the win for the Cubs.
Picks For Cubs vs Reds
- Shota Imanaga to record the win
- Ian Happ over 1.5 hits + runs + RBIs
- Nick Lodolo over 5.5 strikeouts
- Spencer Steer to hit a home run
