Chicago Cubs vs Los Angeles Dodgers Picks and Predictions for Saturday April 25 2026
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The Chicago Cubs travel to face the Los Angeles Dodgers at Dodger Stadium in Los Angeles, California on Saturday, April 25, 2026, with first pitch scheduled for 7:15 PM and coverage available on FOX and MLB.TV. At the time of this writing the odds were not released. This matchup features two of the stronger teams in the league, both carrying impressive records and entering the game with momentum. For a full breakdown of additional matchups, encourage readers to check out free MLB picks.
Starting Pitchers Preview
Chicago is set to start Colin Rea, while Los Angeles will counter with Roki Sasaki. Rea enters with a 3-0 record, posting a 3.00 ERA and a 1.04 WHIP across 24.0 innings. He has allowed 20 hits while striking out 20 batters and walking five, along with surrendering two home runs, showing steady and efficient pitching. On the other side, Sasaki comes in with a 0-2 record and a 6.11 ERA, along with a 1.87 WHIP over 17.2 innings. He has allowed 21 hits, struck out 17, walked 12, and given up four home runs, indicating some struggles with consistency.
Chicago Carrying Strong Form into Los Angeles
Chicago enters this contest with a 16-9 overall record and a 5-4 mark on the road. Their recent stretch has been outstanding, as they recently won over Philadelphia multiple times and also picked up a win over New York, reflecting a team that has been playing at a high level. This consistent success has helped them build momentum heading into this matchup.
From a statistical standpoint, the Cubs are hitting .267 with 139 runs and 230 hits, along with 32 home runs. Their .357 on-base percentage and .427 slugging percentage indicate a highly productive offense. On the pitching side, they hold a 3.44 ERA with a 1.15 WHIP, allowing opponents to hit .223 while striking out 204 batters and issuing 74 walks.
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The key strength for Chicago is its offensive consistency. With a high batting average and strong on-base percentage, the Cubs have shown they can generate scoring opportunities regularly, making them difficult to contain.
Los Angeles Looking to Defend Home Field
Los Angeles comes into this matchup with a 17-8 overall record and a 9-3 mark at home. Their recent stretch has been somewhat mixed, as they recently won over San Francisco and Colorado but also recently lost to San Francisco and Colorado, showing both strong performances and occasional setbacks.
Statistically, the Dodgers are hitting .279 with 137 runs and 237 hits, along with 42 home runs. Their .355 on-base percentage and .473 slugging percentage highlight one of the most productive offenses in this matchup. On the pitching side, they carry a 3.27 ERA with a 1.08 WHIP, allowing opponents to hit .207 while striking out 208 batters and issuing 71 walks.
The biggest strength for Los Angeles is its overall balance. With elite offensive production combined with effective pitching metrics, the Dodgers have consistently found ways to control games.
Cubs vs Dodgers Picks and Prediction
Cubs vs Dodgers Pick
Pick: Cubs Moneyline
Chicago holds the edge in this matchup due to the advantage on the mound. Colin Rea’s lower ERA and WHIP compared to Roki Sasaki suggest he can limit baserunners more effectively and keep the game under control. While Los Angeles has been strong offensively, Sasaki’s struggles with consistency could create opportunities for Chicago’s lineup to capitalize. With strong recent form and consistent offensive production, the Cubs have a solid chance to secure the win.
Cubs vs Dodgers Total Pick
Pick: Over 9.5
I’m leaning toward the over in this matchup because both teams have shown the ability to produce offense at a high level. Chicago’s strong batting average and on-base percentage combined with Los Angeles’ power numbers suggest that runs could come in bunches. Additionally, Sasaki’s higher ERA and WHIP indicate that scoring opportunities may be available. If both lineups perform to their season averages, this game could push past the total.
Final Score Prediction: Chicago Cubs 6 – Los Angeles Dodgers 5
This prediction was written before the completion of game play on Friday.
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