Chicago Cubs vs New York Mets Picks, Prediction, Odds, and Line Movement for Monday June 22 2026

By: Kyle Kargel Published 06/22/2026, 09:41 AM ET
Padres vs Cubs prediction

The Chicago Cubs visit the New York Mets on June 22, 2026, in an interleague matchup where the pitching gap between the two starters is about as wide as you will find anywhere on the board tonight. If you have been following our MLB predictions this season, you understand that a starter with a 9.00 ERA and 1.88 WHIP does not suddenly find himself against a team that has already beaten him in the season series three times. Kodai Senga has been one of the most exploitable arms in the National League in 2026, and tonight he draws a Chicago lineup that leads New York in every major offensive category. Shota Imanaga, meanwhile, has been a model of efficiency with a 1.06 WHIP across 86.2 innings. The public money has been firmly behind Chicago since open, the line has drifted further toward the Cubs throughout the morning, and the over action has been persistent. Here is the complete breakdown before first pitch at Citi Field.

Quick Picks

  • Run Line Pick: Cubs -1.5 (+136)
  • Total Pick: Over 8.5
  • Projected Final Score: Chicago 6, New York 3

Odds and Line Movement

Current Odds

Bet Type Chi. Cubs NY Mets
Moneyline -122 +101
Run Line -1.5 (+136) +1.5 (-164)
Total (Over) 8.5 -114
Total (Under) 8.5 -105

Line Movement - Moneyline

Date Time Chi. Cubs NY Mets Public ($, #)
06/22 05:47:57AM -122 +101 CHC 94%, CHC 71%
06/22 03:40:56AM -120 -101 CHC 94%, CHC 71%
06/21 11:44:15PM -119 -102 CHC 98%, CHC 71%
06/21 10:15:13PM -115 -104 CHC 88%, CHC 69%
06/21 05:19:10PM -112 -108

Line Movement - Total

Date Time Over Under Public ($, #)
06/22 05:47:57AM 8.5 -114 8.5 -105 OV 100%, OV 55%
06/22 03:40:56AM 8.5 -113 8.5 -107 OV 100%, OV 60%
06/21 11:44:15PM 8.5 -110 8.5 -109 OV 100%, OV 57%
06/21 05:19:10PM 8.5 -110 8.5 -110

Cubs vs Mets Key Matchups and Game Preview

Shota Imanaga is the foundation of the Cubs' betting case tonight, and his numbers justify every bit of Chicago's favorite status on the road. Through 86.2 innings this season he carries a 1.06 WHIP with 84 strikeouts, only 22 walks, and 70 hits allowed. The walk rate is exceptional. Issuing 22 walks across nearly 87 innings means Imanaga works ahead in counts, forces hitters to put balls in play on his terms, and minimizes the kind of multi-baserunner half-innings that balloon pitch counts and allow crooked numbers. His 4-6 record is misleading given the underlying efficiency, and his ERA of 4.26 reflects some run support inconsistency rather than a starter who has been getting hit hard.

Against a New York lineup that is hitting .232 as a team with a .297 OBP and 311 runs scored, Imanaga's ability to attack the zone and limit walks creates a significant mismatch. The Mets do not grind at-bats well enough as a unit to pressure a starter with his control profile, and without extended rallies, New York is relying on individual power from Juan Soto to generate runs. Imanaga limiting free passes means Soto rarely comes to the plate with runners on base, which is the single best way to neutralize an elite hitter in a lineup that lacks consistent depth behind him.

Mets

New York's pitching situation is the most important red flag in this matchup, and Kodai Senga's numbers demand serious attention from anyone evaluating this game. He is 0-5 with a 9.00 ERA and a 1.88 WHIP across 24 innings, allowing 28 hits, 17 walks, and seven home runs. A 9.00 ERA at the major league level is not a rough patch or a sequencing issue. It is a fundamental struggle with command and execution that has made Senga one of the most bet-against starters in the National League this season. The 17 walks in 24 innings translate to more than six walks per nine innings, which against a Chicago lineup ranked ahead of New York in every major offensive category is essentially a formula for disaster.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

The Mets do have a legitimate star in Juan Soto, who is posting a .301 average, a .398 OBP, a .575 slugging percentage, 17 home runs, and 38 RBI. Soto's on-base ability is elite and his power gives New York a constant threat even when the lineup around him underperforms. Bo Bichette has also contributed with 42 RBI, providing a second run-production option in the middle of the order. The problem is that the lineup has not been consistent enough to manufacture runs against above-average pitching, and Imanaga is well above average. New York sits at 34-43, has dropped two straight, and the season series against this Cubs club is already 3-0 in Chicago's favor after the Mets allowed 12 runs in the April opener. The current situation shows no structural improvement over those results.

Cubs

The Cubs enter this game as a road favorite for every legitimate reason available. They are 40-37, lead New York in batting average (.244 to .232), runs scored (366 to 311), hits (639 to 598), home runs (90 to 82), OBP (.337 to .297), and slugging percentage (.401 to .372). That is a clean sweep of the offensive categories against a lineup that has already been outscored significantly in the season series. Chicago does not need to manufacture runs in unusual ways tonight. Their lineup is built to punish exactly the kind of pitcher Senga has been in 2026 — a starter who falls behind in counts, walks batters, and leaves elevated fastballs over the middle of the plate that translate into extra-base hits.

Pete Crow-Armstrong has been the Cubs' most complete offensive weapon, posting a .286 average, a .363 OBP, and a .521 slugging percentage that ranks among the best on the roster. Ian Happ leads Chicago with 16 home runs, and Michael Busch anchors the run-production picture with 42 RBI. That combination of power and on-base quality at the top and middle of the order is exactly the profile that thrives against a starter walking more than six batters per nine innings. The run line at +136 offers plus money on a Cubs win by two or more runs, which is the most likely outcome in a game where Chicago's starter is sharp, New York's is not, and the season series has been a one-sided affair from the first meeting.

  • Chicago is 40-37 overall and third in the NL Central.
  • New York is 34-43 overall and has lost two consecutive games in the NL East.
  • The Cubs lead the 2026 season series against the Mets 3-0, with wins of 12-4, 4-2, and 2-1 in April.
  • Chicago leads New York in batting average (.244 to .232), runs scored (366 to 311), OBP (.337 to .297), and slugging (.401 to .372).
  • Senga's 9.00 ERA and 1.88 WHIP across 24 innings make him one of the most exploitable starters in the National League entering tonight.
  • Imanaga's 1.06 WHIP and 22 walks across 86.2 innings represents a stark contrast with Senga's 17 walks in 24 innings.
  • The Cubs moneyline opened at -112 and has steadily moved to -122, a ten-cent move reflecting consistent and growing sharp action on Chicago throughout the overnight and morning.
  • Public dollar percentage on Chicago has held at 94% this morning after reaching 98% overnight, one of the most one-sided markets on today's full slate.
  • The total has held at 8.5 since open with the juice moving from a pick'em to -114 over, reflecting 100% over dollar action across every time stamp with available public data.

Key Injuries and Things To Know - CHC and NYM

  • Kodai Senga (NYM) - Active but struggling: A 9.00 ERA and 1.88 WHIP in 24 innings is not a slump — it is a pattern. Seven home runs allowed and 17 walks issued make Senga a significant liability against a Chicago lineup built for exactly this type of matchup.
  • Tyrone Taylor (NYM) - Out: Outfield depth reduced for New York, limiting lineup flexibility against a sharp starting pitcher.
  • Ronny Mauricio (NYM) - Out: Infield depth reduced, further thinning New York's positional options.
  • Brandon Waddell (NYM) - Out: Bullpen depth limited for the Mets at a time when Senga's early exit is a genuine risk.
  • Joe Jacques (NYM) - Out: Additional reliever unavailable, straining New York's backend depth.
  • Ryan Lambert (NYM) - Out: Further bullpen attrition for the Mets heading into tonight.
  • Riley Martin (CHC) - Out: Bullpen depth reduced for Chicago beyond Imanaga's start.
  • Hunter Harvey (CHC) - Out: Additional reliever unavailable for the Cubs.
  • Daniel Palencia (CHC) - Out: Further bullpen depth limited for Chicago.
  • Season series context: Chicago has outscored New York in the season series and won all three meetings. The 12-4 blowout in the opener reflected exactly what this Cubs offense can do against New York's pitching when they get good at-bats early in the game.

Cubs vs Mets Side and Over/Under Picks

  • Run Line Pick: Chicago Cubs -1.5 (+136) — Getting plus money on a Cubs win by two or more runs against a starter with a 9.00 ERA is the best value position available in this game. Imanaga's WHIP advantage, Chicago's offensive superiority across every major category, the 3-0 season series advantage, and Senga's ongoing command and home run issues all point in the same direction. The run line at +136 is more attractive than the moneyline at -122 because the Cubs have both the pitching to keep New York's score down and the offense to pull away by multiple runs against this starter.
  • Total Pick: Over 8.5 — The juice on the over has moved from -110 at open to -114 on sustained 100% over dollar action, which reflects consistent sharp money identifying Senga's vulnerabilities before the general public fully prices them in. Chicago's lineup will generate runs, and Senga's walk rate and home run tendency almost guarantee a multi-run inning at some point in his start. The over at -114 is the play, and it aligns with the Cubs' run line bet rather than working against it in a projected 6-3 finish.

Final Score Prediction

Chicago Cubs 6, New York Mets 3

Imanaga works six to seven efficient innings, limiting the Mets to two runs on the strength of his elite walk rate and ability to generate weak contact. Senga falls apart in the third or fourth inning when Chicago strings together a combination of walks and extra-base hits, generating a three-run half-inning that puts the game out of reach. The Mets score late against Chicago's depleted bullpen to push the total past 8.5, but the Cubs cover the run line and win their fourth game in this season series without facing serious adversity.

How to Wager on Cubs vs Mets

Tonight's game offers a rare situation where the run line at plus money is the preferred bet over the moneyline on the same team. The Cubs at -1.5 (+136) means you are getting paid a premium to back a team with a significant pitching advantage, a superior lineup, and a 3-0 season series record against the same opponent. That combination almost never comes attached to plus money on the run line, and it reflects the fact that New York's name recognition and home field are keeping the Mets line from drifting further than it already has.

For bettors who want to support game-level analysis like this with data-driven projections, AI picks tools offer a practical layer of confirmation before placing. These platforms generate win probability and run total projections across the full MLB schedule and are particularly useful in games like tonight's where a starter's ongoing struggles create a measurable and persistent edge for the opposing offense.

Two platforms worth reviewing before tonight's game are covered in detail on this site. The Dimers review breaks down a modeling tool that produces game-by-game probability outputs and run total projections, which is directly applicable when you are evaluating a run line and a total in the same game simultaneously. The Oddible review covers an odds-comparison platform that helps you identify where the best number is available before you place. In a game where the Cubs run line has moved from a near pick'em at open to +136, knowing which book is holding the best price on that plus-money number is the difference between capturing maximum value and leaving money on the table.

The plays tonight are Cubs -1.5 at +136 and Over 8.5 at -114. Both bets are built on the same underlying narrative: Senga's command problems create runs, Imanaga limits damage at the other end, and Chicago wins this game decisively enough to cover a two-run spread at plus money.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Cashable No
Video: MLB BEST Picks Today: Guardians vs Rays | MLB Best Bets
MLB BEST Picks Today: Guardians vs Rays | MLB Best Bets
Video: MLB BEST Picks Today: Reds vs Cardinals + Dodgers vs Mets | MLB Best Bets
MLB BEST Picks Today: Reds vs Cardinals + Dodgers vs Mets | MLB Best Bets
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.