Chicago White Sox vs Milwaukee Brewers Picks and Prediction for Sunday March 29 2026
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The Chicago White Sox travel to American Family Field in Milwaukee, Wisconsin to take on the Milwaukee Brewers on Sunday, March 29, 2026, with first pitch scheduled for 2:10 PM and coverage available on MLB.TV. Milwaukee enters this matchup as a -171 favorite on the moneyline while Chicago is listed at +141. The total is set at 8 runs, with the over priced at -103 and the under at -117. On the run line, the White Sox are +1.5 at -156 and the Brewers are -1.5 at +129. Be sure to check out our free MLB picks for more daily baseball betting insight and analysis.
Previous Game Recap & Box Score
The Brewers took care of business again in the previous game, beating the White Sox by a 6-1 final score. Milwaukee jumped out early with three runs in the first inning and added another in the second, which immediately put Chicago in chase mode. The White Sox finally got on the board in the fourth inning, but the Brewers answered later with one run in the sixth and another in the seventh to keep full control. By the end of the afternoon, Chicago had managed one run on seven hits with one error, while Milwaukee finished with six runs on 12 hits and did not commit an error.
Chicago’s hitting summary was again limited, even though the White Sox actually produced seven hits. Munetaka Murakami provided the lone run with a solo home run in the fourth inning, continuing his power-filled start. Chase Meidroth collected two hits and kept his strong average moving in the right direction, while Austin Hays, Travis Peters, Brooks Montgomery, and the rest of the supporting cast added scattered hits that never turned into sustained offense. The White Sox went 0-for-5 with runners in scoring position, and that lack of timely hitting was one of the biggest reasons the offense stalled despite putting a few men on base. Milwaukee’s offense was much more consistent. Brice Turang had three hits and scored twice, Christian Yelich also had three hits and drove in a run, Garrett Mitchell drove in two, Joey Ortiz added an RBI, and Brewer Lockridge chipped in a run batted in as well. The Brewers did not need a home run because they kept pressure on the White Sox throughout the game with contact hitting, baserunning, and steady situational execution.
On the mound, the White Sox got four innings from S. Burke, who allowed seven hits and four runs, three of them earned, while striking out five. The bullpen did not fully settle things, as G. Taylor and B. Hudson each allowed additional runs, and the full staff ended up giving up 12 hits and six runs while walking five. Milwaukee received a strong outing from C. Patrick, who worked 4.1 innings and allowed one earned run on five hits while striking out four. The Brewers bullpen was excellent after that, with A. Ashby earning the win by covering 1.2 scoreless innings and striking out four. A. Zerpa, A. Uribe, and D. Hall also helped close the door, and the Milwaukee staff piled up 11 strikeouts while allowing only one run the entire game.
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The key takeaway is that Milwaukee once again controlled the matchup with cleaner pitching, deeper offense, and better situational execution, while Chicago showed a little more contact than in the earlier loss but still could not generate enough quality offense to challenge the Brewers over nine innings.
Chicago White Sox – Road Form & Team Analysis
The White Sox come into this game with an 0-2 overall record and an 0-2 mark on the road. Chicago recently lost to Milwaukee, recently lost to Milwaukee again, recently lost to the Athletics, recently lost to Seattle, and recently lost to Cincinnati. That stretch paints the picture of a team that has not been able to stop the slide and has struggled badly to find a winning rhythm away from home.
Chicago is batting .129 as a team with two runs, four hits, and two home runs while carrying a .250 on-base percentage and a .323 slugging percentage. On the mound, the White Sox have posted a 14.63 ERA with a 2.75 WHIP, along with 10 walks and just three strikeouts, while allowing opponents to bat .364 against them. Those numbers show a club that has not been able to suppress offense on the other side and has had too few reliable innings from its pitching staff.
The biggest issue for Chicago is that the offense has relied too heavily on isolated power rather than full-lineup production. Murakami’s home run in the previous game gave the White Sox their only run, and Meidroth continued to stand out with another two-hit effort, but the lineup still failed in key spots by going hitless with runners in scoring position. Even when the White Sox manage a few hits, the lack of timely offense and shaky run prevention continue to leave them with too much ground to make up.
Milwaukee Brewers – Home Field Breakdown
Milwaukee enters this game at 2-0 overall and 2-0 at home. The Brewers recently won over Chicago, recently won over Chicago again, recently won over Cincinnati, recently won over Cincinnati again, and recently lost to the Cubs. That recent run shows a team that has responded very well after the loss and has built strong momentum at home.
Milwaukee is batting .364 with 14 runs, 12 hits, and two home runs while posting a .512 on-base percentage and a .606 slugging percentage. The pitching staff has been excellent early, working to a 2.00 ERA and a 1.00 WHIP while striking out 20 and limiting opponents to a .129 batting average. Those team numbers point to a group that has performed well on both sides and has consistently put itself in advantageous spots.
A major edge for Milwaukee has been lineup depth and pressure on the bases. In the previous game, Turang and Yelich each had three hits, Mitchell drove in two, and Ortiz continued his productive start. The Brewers also created stress with stolen bases and aggressive movement, which helped turn solid contact into scoring chances. That blend of offense and steady pitching has made Milwaukee a difficult matchup through the first two games of this series.
Pitching Matchup Breakdown
This pitching matchup features Anthony Kay, a left-handed pitcher wearing number 18 for the White Sox, against Brandon Sproat, a right-handed pitcher wearing number 23 for the Brewers. Kay’s provided numbers come from the 2023 season, when he finished with a 6.14 ERA and a 1.50 WHIP across 14.2 innings between Chicago and New York. In that span he allowed 13 hits, 10 runs, and 10 earned runs while striking out 11 and walking nine. His larger career sample shows a 5.59 ERA and a 1.61 WHIP over 85.1 innings, with opponents batting .269 against him. Sproat’s provided data comes from the 2025 season, when he went 0-2 with a 4.79 ERA and a 1.21 WHIP over 20.2 innings. He allowed 18 hits, 11 runs, and 11 earned runs while striking out 17 and walking seven, with opponents batting .243 against him. Based strictly on the numbers provided, Sproat enters this matchup with the stronger profile in terms of WHIP, opponent batting average, and overall run prevention, while Kay brings a shakier recent statistical background into the game.
Chicago White Sox vs Milwaukee Brewers Pick
Chicago White Sox vs Milwaukee Brewers Spread / Moneyline Pick
The pick in this matchup is the Milwaukee Brewers on the moneyline. Milwaukee has already taken the first two games of the series and has clearly been the better team statistically and on the field. The Brewers have the stronger batting average, on-base percentage, slugging percentage, ERA, WHIP, and strikeout production, and they just backed that up with another decisive win in the previous game. With Sproat also holding the better statistical profile than Kay from the provided data, Milwaukee has the stronger case.
Chicago White Sox vs Milwaukee Brewers Total Pick
I like the under in this game based strictly on the data provided. The total is set at 8, and while Milwaukee has been productive offensively, Chicago’s offense has not shown enough complete lineup production to suggest a big contribution on its side. The White Sox have leaned on solo home run power, and even in a seven-hit game they managed just one run. Milwaukee’s pitching staff has also been very effective early, so I see this game landing on the lower side of the number.
Final Score Prediction: Milwaukee Brewers wins 5–2
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