Chicago White Sox vs Minnesota Twins Picks and Prediction for Tuesday, September 2, 2025

By: David Anicetti Published 09/02/2025, 12:00 AM ET

White Sox Preview

The Chicago White Sox play the second game of a four-game series on the road Tuesday versus the Minnesota Twins. Chicago is 49-88 following Sundayโ€™s 3-2 victory over the New York Yankees, snapping a five-game losing streak. The White Sox are 30.5 games behind first place in the American League Central and well off the pace for postseason contention. The Chicago White Sox and Minnesota Twins are just a few of the baseball teams, make sure you are ready to see all the MLB teams with our free MLB Picks.

Lenya Sosa is batting .269 with 18 home runs, 61 RBI, and 117 hits to lead Chicago in each of the four categories. Miguel Vargas leads Chicago in on-base percentage at .315. Chicago is batting .233 with a .372 slugging percentage. On Tuesday, Chicago will send Davis Martin to the mound. The right-hander is 5-9 with a 4.03 ERA, 85 Ks, and 38 BBs.

Twins Preview

The Minnesota Twins are 62-74 following Sundayโ€™s 7-2 victory over the San Diego Padres. Byron Buxton hit a home run, his 29th of the season, to set a new career best for a single season. Minnesota trails first-place Detroit in the American League Central by 17 games, and the Twins trail the third and final AL wild card spot by 10.5 games.

Byron Buxton is batting .271 with 29 home runs, 70 RBI, and 108 hits to lead Minnesota in each of the full categories. Ryan Jeffers is the leader in on-base percentage at .349. Minnesota is batting .238 with a .397 slugging percentage. On Tuesday, the Minnesota Twins will send Simeon Woods Richardson to the mound. The right-hander is 5-4 with a 4.59 ERA, 71 Ks, and 37 BBs.

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  • Chicago is 1-5 in its last 6
  • The OVER has cashed in 4 of the White Soxโ€™s last 6
  • Minnesota is 5-11 in its last 16
  • The OVER has cashed in each of the Twinsโ€™ last 6

White Sox vs Twins Prediction

Chicago will win on the road Tuesday when visiting Minnesota, but the play here is OVER. The OVER has cashed in four of Chicago's last six and each of Minnesota's last six. Chicago starter Davis Martin gave up two runs on five hits across five innings on August 23 in a 7-3 win over Minnesota, and has allowed eight runs across the last 21.1 innings. Minnesota starter Simeon Woods Richardson has allowed eight runs across the last 8.1 innings. Final Score Prediction: Chicago White Sox win but our best play is OVER 8-4.

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