Chicago White Sox vs New York Yankees Picks and Predictions for Tuesday, September 23, 2025
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The Chicago White Sox visit the New York Yankees on Tuesday at Yankee Stadium and 7:05 PM ET on MLB.TV. Chicago has dropped four of its last five and sits last in the AL Central with a 58–98 record, while New York is 88–68. The Yankees are second in the AL East and have won four of the last five after taking two of three from Baltimore, including a 7–1 win on Sunday. Chicago has been eliminated from postseason contention, while New York is two games behind first place in the AL East and currently holds the first of three AL wild cards. Hit a home run with our free MLB predictions.
Chicago White Sox Preview
Shane Smith makes the start for Chicago with a 6–8 record, 4.06 ERA, and 129 strikeouts in 135.1 innings. Smith’s control has been an issue with 54 walks, though he has limited damage with only 17 home runs allowed. Smith will need to work the strike zone carefully in a tough park for pitchers who fall behind in counts.
At the plate, Lenyn Sosa leads the White Sox with 21 home runs and 71 RBI while batting .259. Miguel Vargas brings a .311 on-base percentage, giving the lineup one of its few consistent bats. The club has scored only 618 runs this season with a .232 average, showing how often they can leave runners on base. Chicago has also struggled away from home, winning just 25 games on the road.
New York Yankees Preview
Luis Gil takes the mound for New York with a 4–1 record and 3.33 ERA across 46.0 innings. He has given up only two home runs, showing good ability to keep the ball in the park, but 29 walks have run up pitch counts. If he keeps his command steady, the Yankees can rely on him through the middle innings.
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New York’s offense remains one of the most dangerous in baseball. Aaron Judge leads the way with 49 home runs, 105 RBI, and a .326 average. Cody Bellinger adds 29 home runs and a .271 average, while Jazz Chisholm Jr. has chipped in 31 home runs and 79 RBI. The Yankees have scored 816 runs and hit 263 homers while holding opponents to a .231 batting average. At 44–31 at home, the Pinstripes continue to control games in the Bronx.
Chicago White Sox vs New York Yankees Prediction
The Yankees have the stronger lineup and better pitching staff. Gil should provide enough innings to set up the bullpen, while Judge and company give New York the advantage at the plate: Chicago’s weak results on the road and lack of steady hitting point to another loss. Final Score Prediction; New York Yankees win 7-2.
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