Cincinnati Reds vs Chicago Cubs Picks and Predictions for Thursday, May 7, 2026

By: Cameron Ross Published 05/07/2026, 01:00 AM ET

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Reds vs Cubs Game Information

The Cincinnati Reds will remain on the road Thursday afternoon for a 2:20 PM match-up inside Wrigley Field in Chicago, IL, for game 3 of 3 against the Chicago Cubs. Cincinnati has 20 wins and 17 losses coming into this matchup, riding a long losing streak that includes the first 3 games of this series. The Chicago Cubs stay home on Thursday with 25 wins and 12 losses, riding a long winning streak after 3 consecutive walk-off victories against the Cincinnati Reds. Stay up to date with our MLB Picks.

Reds Preview

The Cincinnati offense has been below average this season, with a .218 batting average, as the Reds have scored only 147 runs on 260 hits. Cincinnati has compiled a ton of power this year with a .384 team slugging percentage and 48 home runs on the year. Cincinnati's pitching has failed them this season with a 4.45 team ERA. Elly De La Cruz leads the Cincinnati offense this season with a .275 batting average and 10 home runs. Sal Stewart has a .252 batting average along with a team-leading 29 RBI's this season.

Cubs Preview

Offensively, Chicago has been strong enough this season, with a .258 batting average, as the Cubs have scored 193 runs on 318 hits. Chicago has a .352 OBP and a .428 team slugging percentage. Chicago's pitching has carried them this season, with a 3.83 team ERA. Nico Hoerner leads the Chicago offense this season with a .300 batting average and 27 RBI's. Ian Happ has a .234 batting average along with a team-leading 8 home runs this season.

Reds vs Cubs Pitching Matchup

Rhett Lowder will be on the mound Thursday afternoon for game 4 of this series for Cincinnati. This season, Lowder is 3-2 with a 5.09 ERA across 35.1 innings of work. Shota Imanaga will counter for Chicago, looking to improve on his performance thus far this season. Imanaga is 3-2 with a 2.40 ERA across 41.1 innings of action.

Reds vs Cubs Sox Pick

Chicago is the better team in this matchup, playing the better baseball coming into Thursday. Look for the Cubs to use their edge on both sides of the plate to overwhelm a solid Cincinnati team. Take Chicago to continue their winning ways on Thursday as they close this 4-game set with a home win over Cincinnati

Pick: Chicago Cubs
Secondary: Over
Lean: Nico Hoerner Over. 5 Runs

Final Score Prediction: Chicago Cubs win 6-3.

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