Cincinnati Reds vs Philadelphia Phillies Picks and Prediction for Wednesday May 20 2026

By: Kim Smith Published 05/20/2026, 12:25 AM ET
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The Cincinnati Reds and Philadelphia Phillies continue their series on Wednesday May 20, 2026, at Citizens Bank Park in Philadelphia, Pennsylvania. First pitch is scheduled for 1:05 PM ET with coverage on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks at free MLB picks

Starting Pitchers

Andrew Abbott will take the mound for Cincinnati in this matchup. The left-hander enters the game with a 3-2 record, a 4.21 ERA, and a 1.50 WHIP over 51.1 innings pitched. He has allowed 54 hits while striking out 35 batters and walking 23. Philadelphia is expected to counter with Aaron Nola, who comes into the game with a 2-3 record, a 5.91 ERA, and a 1.55 WHIP across 45.2 innings. He has allowed 53 hits while recording 46 strikeouts and 18 walks.

Cincinnati Trying to Stop Recent Slide

The Reds enter Wednesday with a 24-24 overall record and an 11-13 road record. Cincinnati recently lost to Philadelphia 5-4 and also recently lost to Cleveland by scores of 10-3 and 7-4. The Reds did recently win over Cleveland 7-6 and Washington 15-1 during this stretch, but the club has struggled to maintain momentum consistently over the last several games.

Cincinnati is batting .226 as a team with 208 runs scored and 362 total hits this season. The Reds have hit 62 home runs while posting a .311 on-base percentage and a .391 slugging percentage. On the pitching side, Cincinnati owns a 4.82 ERA and a 1.49 WHIP while allowing opponents to hit .252 against them. The pitching staff has also issued 227 walks while recording 368 strikeouts.

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One area that has created problems for Cincinnati has been run prevention. The Reds have allowed at least five runs in three of their last four games and currently hold a 4.82 team ERA. While the offense has shown power with 62 home runs, the pitching staff has struggled to consistently keep opposing lineups under control during this recent stretch.

Philadelphia Carrying Winning Momentum Home

Philadelphia enters this matchup with a 25-23 overall record and a 13-12 home record. The Phillies recently won over Cincinnati 5-4 and have now won five straight games overall. During that run, Philadelphia also recently won over Pittsburgh by scores of 6-0, 6-0, and 11-9 in 10 innings while also recently winning over Boston 3-1. The Phillies have continued to produce solid offensive results while also receiving steady pitching performances during this winning streak.

The Phillies are batting .234 as a team with 204 runs scored and 383 hits this season. Philadelphia has hit 59 home runs while posting a .303 on-base percentage and a .395 slugging percentage. The pitching staff carries a 4.21 ERA and a 1.35 WHIP while opponents are batting .264 against them. Philadelphia has also recorded 458 strikeouts this season, which is the stronger strikeout total between these teams.

One major strength for Philadelphia entering Wednesday is the ability to consistently generate strikeouts on the mound. The Phillies pitching staff has already recorded 458 strikeouts this season while also holding a lower ERA and WHIP than Cincinnati. Philadelphia has also won five consecutive games, showing better overall form entering this matchup.

Cincinnati Reds vs Philadelphia Phillies Picks and Prediction

Cincinnati Reds vs Philadelphia Phillies Pick

  • Pick: Philadelphia Phillies Moneyline

Philadelphia enters this game playing stronger baseball overall with five straight victories, including a win over Cincinnati in the series opener. The Phillies also own the better team ERA and WHIP compared to the Reds while recording significantly more strikeouts on the mound. Cincinnati has struggled recently with multiple losses during this road trip, and the pitching staff has allowed several high-scoring performances. With Philadelphia continuing to play well at both the plate and on the mound, the Phillies hold the edge in this matchup.

Cincinnati Reds vs Philadelphia Phillies Total Pick

  • Pick: Take the over if the total is set at 9

I would lean toward the over in this matchup because both starting pitchers enter with elevated ERA and WHIP numbers. Cincinnati’s pitching staff has allowed at least five runs in three of its last four games, while Philadelphia’s starter enters with a 5.91 ERA. Both offenses also have shown home run power this season, with Cincinnati hitting 62 homers and Philadelphia adding 59. With recent games involving both teams producing offense consistently, this matchup has the potential to become another higher-scoring contest.

Final Score Prediction: Philadelphia Phillies 6 – Cincinnati Reds 4

This prediction was written before the completion of game play on Tuesday.

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