Cincinnati Reds vs St. Louis Cardinals Picks and Predictions for Saturday, July 25, 2026

By: Cameron Ross Published 07/25/2026, 12:45 AM ET

Reds vs Cardinals Game Information

The Cincinnati Reds continue a road trip Saturday night with a 7:15 PM Game inside Busch Stadium in St. Louis, MO, against the Saint Louis Cardinals. Cincinnati is 6 games below .500 this season, having won 4 of the last 5, including 3 in a row after the win in Game 1 of this set. The Saint Louis Cardinals stay home Saturday, 1 game above .500, but they have dropped 4 of the last 5, including 2 in a row. Stay up to date with our MLB Picks.

Reds Preview

The Cincinnati Reds have a .230 batting average this season, scoring 423 runs on 777 hits. Cincinnati has a .309 OBP and a .400 team slugging percentage. The Reds pitching has struggled this year with a 4.56 team ERA. Elly De La Cruz leads Cincinnati with a .276 batting average. Sal Stewart has a .251 batting average and leads the team with 21 home runs and 75 RBIs.

Cardinals Preview

The St. Louis Cardinals have a .241 batting average this season, scoring 454 runs on 823 hits. St. Louis has a .317 OBP and a .384 team slugging percentage. The Cardinals pitching has been mediocre with a 4.12 team ERA this year. Jordan Walker leads the St. Louis offense with a .288 batting average, 22 home runs, and 77 RBIs.

Reds vs Cardinals Pitching Matchup

Hunter Greene will take the mound Saturday for Cincinnati, looking to settle in after a difficult start to his season. Greene is 2-1 with a 6.06 ERA Β through 16.1 innings. Andre Pallante will counter for St. Louis, looking to earn his 11th victory. Pallante is 10-6 this year with a 4.02 ERA through 105.1 innings of work

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Reds vs Cardinals Pick

The St. Louis Cardinals have the more reliable starting pitcher and will take advantage of playing at home Saturday. Look for the Cardinals offense to do the work Saturday, leading St. Louis to a divisional victory.

  • Pick: St. Louis Cardinals
  • Secondary: Over
  • Lean: Jordan Walker Over 1.5 Total Bases

Final Score Prediction: St. Louis Cardinals win 6-4.

Β Game Written Before completion of the game on Friday.

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