Cleveland Guardians vs Boston Red Sox Picks and Prediction for Tuesday September 2 2025

By: Eddie Kline Published 09/02/2025, 01:00 AM ET

Historic Fenway Park will play host to a Tuesday night MLB clash between the Cleveland Guardians and the Boston Red Sox. Be ready for the baseball season with all of our MLB predictions. The Guardians (68-68) have dropped six of their last ten games and are four games back in the race for the final AL Wild Card spot. On Monday, leadoff hitter Steven Kwan collected three of Cleveland’s eight hits during a 6-4 road loss against Boston.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Guardians Preview

Twenty-six year old righty Slade Cecconi (5-6 4.41 ERA) will head to the hill for the Guardians in this contest. Through 102 innings of work, Cecconi has surrendered 20 long balls and owns a respectable 1.26 WHIP.The Boston Red Sox have won 43 of their first 70 home games and are sitting in second place in the AL Wild Card standings. During Monday’s home victory, Boston SS Trevor Story went 3-for-4 with a home run and drove in a pair of runs. Rookie OF Roman Anthony added two hits and scored a run for the Red Sox, who improved to 77-62 overall.

Red Sox Preview

Boston manager Alex Cora will give the nod to talented left-hander Garrett Crochet (14-5 2.40 ERA) on Tuesday. Last time out, Crochet (6 IP) allowed two runs and retired seven batters by strikes during a 3-2 road victory against Baltimore.

Red Sox vs Guardians Pick

Boston OF Wilyer Abreu (calf) has resumed running sprints and should rejoin the lineup this week. Through 136 games, Cleveland ranks 29th in OPS and 28th in runs scored. For the season, Boston ranks 9th in OPS and 5th in runs scored. Take the under. Final Score Prediction, Boston Red Sox win 5-1.

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA) 21+ only. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). Rewards are non-withdrawable bonus bets that expire in 7 days. In partnership with Kansas Crossing Casino and Hotel. See BetMGM.com for Terms. US promotional offers not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.

Wagering 1x Bonus

Odds Requirements -500

Cashable Yes

Whatever the moment. It’s Never Ordinary at bet365. That’s why if you sign up now you will receive $150 in Bonus Bets Win or Lose when you bet $5! Minimum $10 deposit required. Minimum odds -500 of greater. Bonus Bets wager excluded from returns. New customers only. T&CS, time limits and exclusions apply. GAMBLING PROBLEM? CALL OR TEXT 1-800-GAMBLER (AZ/CO/IL/IN/KS/KY/LA/MD/NC/NJ/OH/PA/TN/VA) or 1-800-BETS OFF (IA). 21+ (18+ KY). Must be present in AZ/CO/IA/IL/IN/KS/KY/LA (select parishes)/MD/NC/NJ/OH/PA/TN/VA.

Min. Deposit $5

Wagering 1x Deposit

Cashable No

Gambling Problem? Call 1-800-GAMBLER or visit RG Help . Call 1-888-789-7777 or visit Helpline and Chat – CONNECTICUT COUNCIL (CT). Hope is here. Home or call (800) 327-5050 for 24/7 support (MA). Visit Home (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ D.C.) and present in select states (for KS, in affiliation with Kansas Star Casino). First online real money wager only. $5 first deposit required. Bonus issued as nonwithdrawable bonus bets which expire 7 days after receipt. See terms at FanDuel Sportsbook