Cleveland Guardians vs Houston Astros Picks and Predictions for Saturday, June 20, 2026

By: Cameron Ross Published 06/20/2026, 12:20 AM ET

Guardians vs Astros Game Information

The Cleveland Guardians stay on the road Saturday night for a 7:15 PM matchup at Dalkin Park in Houston, TX, against the Houston Astros. Cleveland has 40 wins and 36 losses this season, coming into Saturday with 3 losses in the last 5 after a 6-run loss in Game 1 of this series. The Houston Astros stay home Saturday, 5 games below .500, but ride a 3-game winning streak into this matchup. For other MLB news, see our MLB Picks.

Guardians Preview

The Cleveland offense has a .229 batting average this season, scoring 298 runs on 562 hits. Cleveland has a .315 OBP and a .370 team slugging percentage. Cleveland's pitching has been the team's biggest strength this year, with a 3.79 team ERA, but they have allowed 20 runs over their last 3 losses. Brayan Rocchio leads the Cleveland offense this season with a .273 batting average. Angel Martinez has a .239 batting average and leads the team with 11 home runs. Chase DeLauter has a .263 batting average and leads Cleveland with 34 RBI's.

Astros Preview

The Houston Astros offense has compiled a .243 batting average and has scored 344 runs on 621 hits this season. Houston has a .318 OBP and a .412 team slugging percentage. Houston's pitching has been the team's biggest issue this year, with a 4.87 ERA, but they have allowed just 7 runs across their current 3-game winning streak. Yordan Alvarez does it all for the Houston offense, leading the team with a .324 batting average, 24 home runs, and 55 RBI's.

Guardians vs Astros Pitching Matchup

Joey Cantillo will be on the mound for Cleveland on Saturday, looking to end their recent woes. Cantillo is 5-3 this year with a 4.38 ERA over 72 innings. Spencer Arrighetti will counter for Houston. This season, Arrighetti is 7-2 overall with a 2.57 ERA over 63 innings.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Guardians vs Astros Sox Pick

Houston is playing the better baseball coming into this matchup and will have the edge on both sides of the dish. Look for Houston to extend their winning streak Saturday as they overwhelm a struggling Cleveland team. Take the Astros to extend their winning streak to 4 games as they win Game 2 of this series at home.

  • Pick: Houston Astros -143
  • Secondary: Β Over 8.5
  • Lean: Yordan Alvarez Over 1.5 Bases

Final Score Prediction:Β  Houston Astros win 7-4.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $150 in Bonus Bets *Paid Within 14 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Cashable No
Video: MLB BEST Picks Today: Guardians vs Rays | MLB Best Bets
MLB BEST Picks Today: Guardians vs Rays | MLB Best Bets
Video: MLB BEST Picks Today: Reds vs Cardinals + Dodgers vs Mets | MLB Best Bets
MLB BEST Picks Today: Reds vs Cardinals + Dodgers vs Mets | MLB Best Bets
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.