Cleveland Guardians vs Seattle Mariners Picks and Prediction for Saturday March 28 2026
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The Cleveland Guardians travel to T-Mobile Park in Seattle, Washington, to take on the Seattle Mariners on Saturday, March 28, 2026, with first pitch scheduled for 9:40 PM. The game will be televised on MLB.TV and MLB Net. Seattle enters this matchup as the moneyline favorite at -194, while Cleveland is listed at +159. The total is set at 7 runs, and the run line shows Cleveland at +1.5 (-136) and Seattle at -1.5 (+113). Be sure to check out our free MLB picks for more daily baseball analysis and predictions.
Previous Game Recap & Box Score
The previous game in this series ended with the Seattle Mariners earning a 5-1 win over the Cleveland Guardians. It was a game that stayed tight early because Cleveland grabbed a 1-0 lead in the opening inning, but Seattle responded with three runs in the fourth inning and then added two more in the sixth to take control. Cleveland finished with 1 run on 4 hits and did not commit an error, while Seattle scored 5 runs on only 3 hits and also played a clean defensive game. Even though the Guardians produced one more hit than the Mariners, Seattle made far more of its limited opportunities and turned a small number of hits into enough offense to secure the win.
Cleveland’s offense centered almost entirely around Chase DeLauter, who hit a solo home run in the first inning and drove in the team’s only run. Steven Kwan added two hits, and Bo Naylor also collected a hit, but the rest of the lineup had trouble generating sustained pressure. The Guardians stranded six runners and went hitless in their limited opportunities with runners in scoring position. For Seattle, Luke Raley and Cole Young delivered the decisive swings. Raley homered and drove in two runs, while Young added a three-run home run and finished with three runs batted in. Leo Rivas added a triple, and the Mariners made the most of a lineup that produced only three hits but still pushed across five runs.
On the mound, Cleveland got five innings from Gavin Williams, who allowed 3 runs on 2 hits while striking out 7, but his six walks created too many traffic situations and put him in trouble. Cade Holderman followed and gave up 2 more runs in his inning, including another home run, while Paul Pallette worked two scoreless innings with no hits allowed. Seattle received a strong outing from George Kirby, who went six innings and allowed just 1 earned run on 2 hits while striking out 6 and walking 2. The Mariners bullpen followed with three scoreless innings, as Eduard Bazardo, Matt Brash, and Andres Munoz combined to allow just 2 hits and close the game out efficiently.
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The key takeaway from the previous result is that Seattle showed an ability to win even without a high hit total because its power and situational scoring made the difference, while Cleveland could not build enough offense behind DeLauter’s early home run despite solid contact from a few hitters.
Cleveland Guardians – Road Form & Team Analysis
The Guardians enter this game at 1-1 overall and 1-1 on the road. Cleveland has recently lost to Seattle, recently won over Seattle, recently won over Arizona twice, and recently won over Cincinnati. That recent stretch still reflects a club that has played well overall, even though it was slowed down in the most recent game of this series.
Cleveland has posted strong team numbers so far, batting .316 with 6 runs, 12 hits, and 2 home runs. The Guardians have a .366 on-base percentage and a .579 slugging percentage, which shows that the offense has been productive when it gets going. On the pitching side, Cleveland owns a 4.00 ERA and a 0.89 WHIP, with 14 strikeouts, just 2 walks, and a .188 opponent batting average.
The strength of this team has been its ability to combine contact hitting with efficient pitching, but the previous game showed that the lineup can still become overly dependent on one or two bats if the middle of the order does not produce. Chase DeLauter continued his strong start with another home run, and Steven Kwan had a two-hit game, but Cleveland finished with only one run because it could not turn enough traffic into bigger innings.
Seattle Mariners – Home Field Breakdown
The Mariners come into this game at 1-1 overall and 1-1 at home. Seattle has recently won over Cleveland, recently lost to Cleveland, recently lost to San Diego, recently won over the White Sox, and recently lost to the Cubs. That recent run shows a team that has been uneven overall but has already shown it can win this matchup at home.
Seattle’s team stats tell an unusual story through two games. The Mariners are batting .188 with 4 runs, 6 hits, and 4 home runs. Their on-base percentage sits at .235, but their slugging percentage is a strong .625 because so much of their offense has come through the long ball. On the mound, Seattle has a 6.00 ERA and a 1.56 WHIP, with 11 strikeouts, 2 walks, and a .316 opponent batting average.
The key edge for Seattle right now is power. Even though the Mariners are not piling up hits, they are getting game-changing swings from Luke Raley and Cole Young, and that helped them flip the previous game despite being outhit. If Seattle continues to turn a small number of scoring chances into home runs, it will stay dangerous in this series.
Pitching Matchup Breakdown
Cleveland will turn to Joey Cantillo, a left-handed pitcher wearing number 54, while Seattle counters with Bryan Woo, a right-handed pitcher wearing number 22. Cantillo’s 2025 season line showed a 5-3 record with a 3.21 ERA and a 1.26 WHIP across 95.1 innings. He struck out 108 batters, walked 42, allowed 78 hits, and surrendered 10 home runs. His opponent batting average was .218, and his expanded numbers showed a strong strikeout rate with 10.2 strikeouts per nine innings. Woo was outstanding in 2025, going 15-7 with a 2.94 ERA and a 0.93 WHIP over 186.2 innings. He struck out 198 batters, walked just 36, allowed 137 hits, and gave up 26 home runs. Opponents hit only .200 against him, and his WHIP ranked among the best based on the data provided. Based strictly on the numbers here, Seattle has the edge in the pitching matchup because Woo enters with the lower ERA, the lower WHIP, the stronger win-loss record, and excellent strikeout production over a much larger workload.
Cleveland Guardians vs Seattle Mariners Pick
Cleveland Guardians vs Seattle Mariners Spread / Moneyline Pick
The pick in this matchup is the Seattle Mariners on the moneyline. Seattle took the previous game despite recording only three hits because its lineup delivered in the biggest moments, and the Mariners now send Bryan Woo to the mound after a 2025 season in which he posted a 15-7 record, a 2.94 ERA, and a 0.93 WHIP. Cleveland has stronger early team batting numbers, but the Guardians were held to one run in the most recent game and now face a pitcher whose overall profile is stronger than Joey Cantillo’s. Cantillo had a solid 2025 season, but Woo’s edge in ERA, WHIP, strikeout total, and overall run prevention makes Seattle the better side based on the data provided.
Cleveland Guardians vs Seattle Mariners Total Pick
I like the under in this matchup because the total is set at 7 and both starting pitchers bring solid numbers into the game. Cantillo posted a 3.21 ERA and held opponents to a .218 batting average in 2025, while Woo was even sharper with a 2.94 ERA, a 0.93 WHIP, and a .200 opponent batting average. Cleveland’s offense has been productive overall, but it scored only once in the last game, and Seattle has relied heavily on home run production rather than a steady flow of hits. With two pitchers who have shown they can limit damage and a matchup that could be defined by a few big swings instead of constant scoring, I like this game to stay under the total.
Final Score Prediction: Seattle Mariners win 4–2
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