Colorado Rockies at San Francisco Giants Picks and Predictions for Sunday, September 28, 2025

By: David Anicetti Published 09/28/2025, 12:00 AM ET
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The Colorado Rockies visit the San Francisco Giants on Sunday at Oracle Park at 3:05 PM ET on MLB.TV in the final game of the regular season. Colorado lost 6–3 on Friday and sits last in the NL West at 43–117, including 18–61 on the road. San Francisco won that game to move to 79–81, third in the division with a 40–39 home record. Colorado and San Francisco will both miss the postseason. Hit a home run with our free MLB best bets.

Colorado Rockies Preview

Colorado will turn to rookie McCade Brown on Sunday. Brown is 0–4 with a 7.54 ERA in 22.2 innings and has given up 15 walks along with 26 hits. The Rockies’ bullpen has not been much better, and as a staff, the Rockies have a 6.00 ERA, so getting through each inning has been a season-long problem.

At the plate, Hunter Goodman has been the main source of power with 30 home runs and 90 RBI while hitting .276. The rest of the lineup has struggled to get on base with a .293 team on-base percentage. Colorado has dropped four of its last five games and has been weak in day games, going 18–42.

San Francisco Giants Preview

San Francisco hands the ball on Sunday to Logan Webb. He is 14–11 with a 3.30 ERA across 201.2 innings. Webb has piled up 216 strikeouts while issuing only 46 walks. He has been steady all year and usually works deep into games, which helps the bullpen stay rested and be ready for an inning or two of work.

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Willy Adames leads the Giants with 29 home runs and 86 RBI, while Jung Hoo Lee leads with a .264 average and .326 on-base percentage. Heliot Ramos has added 158 hits. As a team, the Giants are batting .235 with 170 homers, and the pitching staff has been reliable with a 3.87 ERA. The Giants are 40-39 at home, winning three of the last five.

Colorado Rockies vs San Francisco Giants Prediction

The Giants have the better starter on the mound and more balance in the lineup. Colorado’s pitching struggles and a lack of run support make it tough to stay close against any opponent. San Francisco should control this game and end the regular season with a win. Final Score Prediction: San Francisco Giants win 5–2.

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