Colorado Rockies vs Arizona Diamondbacks Picks and Prediction for Saturday May 23 2026

By: Kim Smith Published 05/23/2026, 12:50 AM ET
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The Colorado Rockies travel to face the Arizona Diamondbacks on Saturday, May 23, 2026, at Chase Field in Phoenix, Arizona. First pitch is scheduled for 10:10 PM ET with television coverage available on MLB.TV. Colorado enters the matchup with a 19-32 overall record and a 9-17 road mark, while Arizona comes into the contest at 26-23 overall with a strong 16-9 home record. ESPN Analytics heavily favors the Diamondbacks entering this matchup with a 66.8 percent projection advantage. Be sure to check out our free MLB picks at free MLB picks

Starting Pitchers Preview

Michael Lorenzen gets the start for Colorado carrying a 2-6 record with a 7.03 ERA and a 1.91 WHIP across 48.2 innings this season. Lorenzen has allowed 76 hits and nine home runs while striking out 36 batters. Arizona counters with Zac Gallen, who enters with a 2-4 record and a 4.78 ERA over 49.0 innings. Gallen has allowed 55 hits while recording 34 strikeouts and giving up seven home runs this season.

Rockies Trying to End Difficult Stretch

Colorado enters this matchup with a 19-32 overall record and has struggled away from home with only nine road victories this season. The Rockies recently lost to Arizona 2-1 after previously recently lost to Texas by scores of 5-4 and 10-0. Before those games, Colorado recently won over Texas 7-6 but also recently lost to Arizona 8-6. The Rockies have now dropped four of their last five games while struggling to consistently produce offense during that stretch.

Colorado is batting .243 as a team with 211 runs scored, 417 hits, and 44 home runs this season. The Rockies own a .311 on-base percentage and a .383 slugging percentage while carrying a 4.94 ERA and a 1.47 WHIP. Opponents are batting .275 against Colorado pitching, and the staff has recorded 378 strikeouts this season.

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One major issue for Colorado entering this matchup is pitching consistency. The Rockies own the higher ERA, higher WHIP, and higher opponent batting average compared to Arizona. Colorado has also allowed at least five runs in three of the last five games, putting additional pressure on the offense to keep pace.

Arizona Continuing Strong Home Form

Arizona enters this game with a 26-23 overall record and has played very well at home with a 16-9 record at Chase Field. The Diamondbacks recently won over Colorado 2-1 after previously recently won over San Francisco by scores of 6-3, 5-3, and 12-2. Arizona also recently won over Colorado 8-6 before the current stretch against San Francisco. The Diamondbacks have now won five straight games entering Saturday night and have allowed only 15 total runs during that span.

The Diamondbacks are batting .244 as a team with 223 runs scored, 397 hits, and 44 home runs this season. Arizona owns a .311 on-base percentage and a .399 slugging percentage while posting a 4.17 ERA and a 1.26 WHIP. The pitching staff has held opponents to a .241 batting average while recording 357 strikeouts this season.

Arizona’s biggest strength entering this matchup is overall balance. The Diamondbacks hold advantages over Colorado in ERA, WHIP, opponent batting average, and slugging percentage. Arizona has also shown recent consistency both offensively and defensively during the current five-game winning streak.

Colorado Rockies vs. Arizona Diamondbacks Picks and Prediction

Colorado Rockies vs. Arizona Diamondbacks Pick

  • Pick: Arizona Diamondbacks Moneyline

Arizona enters this matchup with stronger recent momentum and clear pitching advantages across multiple categories. The Diamondbacks have won five straight games while Colorado has dropped four of the last five. Arizona also owns the lower ERA, lower WHIP, and lower opponent batting average entering this contest. Playing at home where the Diamondbacks are 16-9 this season gives Arizona another edge against a Colorado team that has struggled away from home.

Colorado Rockies vs. Arizona Diamondbacks Total Pick

  • Pick: Over 9.0

I would lean toward the over because Colorado’s pitching staff has struggled throughout the season, carrying a 4.94 ERA and allowing opponents to hit .275 against them. Arizona has also scored at least five runs in four of the last five games while producing 33 total runs during the current winning streak. Even though Arizona’s pitching numbers are stronger overall, Colorado has still shown occasional offensive upside, including six runs against Arizona earlier in the week.

Final Score Prediction: Arizona Diamondbacks 7 – Colorado Rockies 4

This prediction was written before the completion of game play on Friday.

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