Colorado Rockies vs Arizona Diamondbacks Picks and Prediction for Sunday May 24 2026

By: Kim Smith Published 05/24/2026, 12:25 AM ET
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The Colorado Rockies travel to Chase Field in Phoenix for a matchup against the Arizona Diamondbacks on Sunday, May 24, 2026. First pitch is scheduled for 4:10 PM ET with coverage available on MLB.TV. Colorado enters the game with a 20-32 overall record while Arizona comes into the matchup at 26-24 on the season. At the time of this writing the odds were not released. Be sure to check out our free MLB picks

Starting Pitchers Taking the Ball

Jose Quintana gets the start for Colorado in this matchup. The left-hander enters with a 2-2 record, a 4.08 ERA, and a 1.41 WHIP across 39.2 innings pitched. He has allowed 39 hits and six home runs while striking out 20 batters and walking 17 this season. Arizona counters with Ryne Nelson, who comes into the game with a 1-3 record along with a 5.19 ERA and 1.19 WHIP over 52 innings pitched. Nelson has allowed 46 hits and 11 home runs while recording 46 strikeouts and 16 walks this year.

Rockies Attempting to Build Off Recent Victory

Colorado enters this game with a 20-32 overall record and a 10-17 road mark this season. The Rockies recently won over Arizona 3-2 after splitting the first two games of the series. Before arriving in Phoenix, Colorado recently lost to Texas twice but also recently won over the Rangers 7-6 in a close contest at home. The Rockies have alternated wins and losses throughout the last several games while continuing to search for consistency.

Colorado is batting .244 as a team with 214 runs scored, 426 hits, and 44 home runs this season. The Rockies have posted a .311 on-base percentage and a .381 slugging percentage while striking out 381 times offensively. On the mound, Colorado owns a 4.88 ERA with a 1.46 WHIP while opponents are batting .274 against the pitching staff.

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One of the challenges for Colorado this season has been run prevention. The Rockies have allowed opponents to hit .274 against them while carrying a 4.88 ERA and 1.46 WHIP as a pitching staff. However, the offense has shown the ability to remain competitive with 426 hits and balanced production throughout the lineup.

Diamondbacks Hoping to Regain Momentum at Home

Arizona enters this matchup with a 26-24 overall record and a strong 16-10 record at home this season. The Diamondbacks recently lost to Colorado 3-2 but had previously recently won over Colorado, San Francisco twice, and also recently won over the Giants 12-2 during a productive stretch. Arizona has won four of its last five games overall and continues to play solid baseball at home.

The Diamondbacks are batting .244 as a team with 225 runs scored, 404 hits, and 44 home runs this season. Arizona owns a .311 on-base percentage and a .397 slugging percentage while posting a 4.14 ERA and 1.26 WHIP on the pitching side. Opponents are batting .241 against Arizona pitching, and the staff has recorded 361 strikeouts this year.

One of the biggest strengths for Arizona entering this game is the balance between the offense and pitching staff. The Diamondbacks have matched Colorado’s batting average while producing more runs and maintaining much stronger pitching numbers overall. Arizona’s ability to limit opposing hitters to a .241 batting average has also helped the club remain effective at home this season.

Colorado Rockies vs. Arizona Diamondbacks Picks and Prediction

Colorado Rockies vs. Arizona Diamondbacks Pick

  • Pick: Arizona Diamondbacks Moneyline

Arizona enters this matchup with the stronger overall record, the better home performance, and more reliable pitching numbers throughout the season. The Diamondbacks have won four of their last five games overall and continue to perform well offensively while limiting opponents more effectively on the mound. Colorado recently won over Arizona in the previous game, but the Rockies have struggled on the road this year and continue to carry a higher ERA and WHIP. I believe Arizona responds with a stronger effort at home Sunday.

Colorado Rockies vs. Arizona Diamondbacks Total Pick

  • Pick: Over 8.5

I am leaning toward the over in this matchup because both starting pitchers enter with ERAs above 4.00 and both teams have shown the ability to score runs recently. Colorado owns a 4.88 team ERA, while Arizona starter Ryne Nelson has allowed 11 home runs already this season. The Diamondbacks have scored at least five runs in three of their last five games, and Colorado has also been involved in several higher-scoring contests recently. This matchup feels likely to produce enough offense to push the total upward.

Final Score Prediction: Arizona Diamondbacks 6 – Colorado Rockies 4

This prediction was written before the completion of game play on Saturday.

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