Colorado Rockies vs Houston Astros Picks and Predictions for Wednesday, April 15, 2026
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The Colorado Rockies visit the Houston Astros at Daikin Park on Wednesday, April 15 at 8:10 PM ET on MLB.TV. Colorado is 6-10, fourth in the NL West, while Houston is 6-11, fifth in the AL West. The Rockies lost 7-2 to the Padres in their most recent game, while the Astros fell 6-2 to the Mariners. This is the second game of a three-game series, with Colorado holding a 3-0 edge in the season series. Build your bankroll with our free MLB picks.
Colorado Rockies Preview
The Rockies lost 7-2 to San Diego in their most recent game and have now dropped four straight. Colorado has struggled on the road, where the team is just 2-8, and runs allowed have been an issue during this stretch.
Colorado is hitting .237 with a .299 on-base percentage and .375 slugging percentage. TJ Rumfield leads the team with a .308 average, while Mickey Moniak has provided power with five home runs and nine RBI. The lineup has some production, but it has not been consistent enough to overcome pitching issues.
On the mound, Colorado has a 4.27 ERA and 1.36 WHIP while allowing a .258 opponent average. The staff has struggled to limit contact and has allowed steady traffic on the bases, which has led to extended innings. That has been a major factor in recent losses.
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Injuries: Jose Quintana, 15-Day IL, Jared Thomas, 7-Day IL, Kyle Freeland, Day-To-Day, McCade Brown, 60-Day IL, Case Williams, 60-Day IL
Houston Astros Preview
The Astros lost 6-2 to Seattle in their most recent game and have now dropped eight straight. Houston has struggled across the board during this stretch, particularly on the mound, which has made it difficult to stay competitive.
Houston is hitting .272 with a .364 on-base percentage and .441 slugging percentage, giving them a clear offensive edge in this matchup. Yordan Alvarez leads the team with a .321 average, six home runs, and 14 RBI, while Jose Altuve is hitting .311 and continues to get on base at a high rate. The lineup has been productive, even during the losing streak.
The problem has been pitching. Houston has a 6.50 ERA and 1.71 WHIP, both among the worst marks in the league, while allowing a .271 opponent average. The staff has issued 97 walks, which has created constant pressure and led to high-scoring games.
Injuries: Bennett Sousa, 15-Day IL, Glenn Otto, Day-To-Day, Cody Bolton, Day-To-Day, Jeremy Pena, 10-Day IL, Josh Hader, 15-Day IL
Pitching Matchup
Colorado Rockies
Colorado has not officially named a starter for this game. Team ERA 4.27 and WHIP 1.36
Houston Astros
Houston has also not announced a starting pitcher. Team ERA 6.50 and WHIP 1.71.
Colorado Rockies vs Houston Astros Prediction
Houston has the advantage due to the stronger offense, even with recent struggles. The Astros have been more productive at the plate and should be able to take advantage of Colorado’s pitching issues. While both teams have struggled, Houston’s lineup gives them the better chance to break through, despite struggling on the mound. Houston’s bats will be the difference. Final Score Prediction: Houston Astros win 6-4.
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