Houston Astros vs Seattle Mariners Picks and Predictions for Monday, April 13, 2026

By: David Anicetti Published 04/13/2026, 12:00 AM ET
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The Houston Astros visit the Seattle Mariners at T-Mobile Park on Monday, April 13, at 4:10 PM ET on MLB.TV. Houston is 6-9, fourth in the AL West, while Seattle is also 6-9 and tied for fourth in the division. This game will conclude a four-game series between the two teams, with Seattle leading the series 2-0 entering Sunday’s third game. The Astros lost 8-7 to the Mariners in their most recent game. Find value with our free MLB picks.

Houston Astros Preview

The Astros lost 8-7 to Seattle in their most recent game and have now dropped six straight, including the first two games of this series. Houston has produced enough offense to stay competitive, but the inability to limit runs has defined this losing streak.

Houston is hitting .281 with a .377 on-base percentage and .462 slugging percentage, making it one of the more productive offenses early in the season. Yordan Alvarez leads the team with a .360 average, six home runs, and 14 RBI, while Jose Altuve and Cam Smith are both hitting over .300. The lineup has consistently created scoring chances and has not been the issue.

The concern is pitching. Houston has a 6.47 ERA and 1.68 WHIP, allowing a .265 opponent average and issuing 87 walks. That level of baserunners has made it difficult to hold leads or keep games within reach, even when the offense performs well.

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Injuries: Jeremy Pena, Day-To-Day, Christian Walker, Day-To-Day, Cody Bolton, Day-To-Day, Glenn Otto, Day-To-Day, Bennett Sousa, 15-Day IL

Seattle Mariners Preview

The Mariners are coming off an 8-7 win over Houston and have taken the first two games of this series. Seattle has now won two straight after a three-game losing streak and has been more effective at home, where they are 5-4 this season.

Seattle is hitting .193 with a .302 on-base percentage and .323 slugging percentage, showing ongoing struggles at the plate. Cole Young leads the team with a .269 average, while Luke Raley has three home runs, and Cal Raleigh leads with 10 RBI. The offense has not been consistent, but it has done enough in key moments during this series.

Pitching has been the strength. The Mariners have a 3.14 ERA and 1.07 WHIP, allowing a .229 opponent average while striking out 134 and walking just 34. That ability to limit baserunners and control innings has allowed Seattle to stay competitive despite lower offensive production.

Injuries: Brendan Donovan, Day-To-Day, Miles Mastrobuoni, 10-Day IL, Victor Robles, 10-Day IL, Bryce Miller, 15-Day IL, Teddy McGraw, Out

Pitching Matchup

Houston Astros – Mike Burrows

Burrows is 1-2 with a 5.63 ERA and 1.75 WHIP over 16.0 innings. He has allowed 22 hits and has struggled to limit baserunners consistently.

Seattle Mariners – George Kirby

Kirby is 1-2 with a 3.60 ERA and 0.90 WHIP across 20.0 innings. He has allowed just 13 hits and has shown strong command early in the season.

Houston Astros vs Seattle Mariners Prediction

Seattle has the advantage with stronger pitching and better recent results in this series. Houston continues to struggle on the mound, and that has been the difference in most games. Even with the Astros’ offensive production, pitching favors Seattle, and the Mariners will continue to make Astros’ hitters swing and miss. Final Score Prediction: Seattle Mariners win 5-4.

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