Houston Astros vs Seattle Mariners Picks and Predictions for Sunday April 12 2026

By: Kim Smith Published 04/12/2026, 12:10 AM ET
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The Houston Astros travel to T-Mobile Park in Seattle, Washington, to take on the Seattle Mariners on Sunday, April 12, 2026. First pitch is scheduled for 4:10 PM ET with coverage available on MLB.TV. At the time of this writing the odds were not released. This matchup features two teams looking to improve their recent form, and readers should be sure to check out free MLB picks for more daily insights.

Starting Pitchers for This Matchup

The Astros have not yet announced a starting pitcher for this game. On the other side, Logan Gilbert will take the mound for Seattle, entering with an 0-2 record, a 5.40 ERA, and a 1.26 WHIP across 16.2 innings. He has allowed 18 hits while striking out 18 and walking just 3, giving up 1 home run so far this season.

Astros Trying to Stop a Tough Stretch on the Road

Houston enters this contest with a 6-8 overall record and a difficult 1-6 mark on the road. The Astros have struggled recently, going 0-5 over their last five games, including a recent loss to Seattle. Prior to that, they dropped multiple games to Colorado and also lost a high-scoring contest to Oakland, showing that they have not been able to find consistent results during this stretch.

From a statistical standpoint, Houston has been productive offensively despite the recent losses. They are hitting .270 with 85 runs scored and 130 hits, along with 17 home runs. Their on-base percentage sits at .372, and their slugging percentage is .449. On the pitching side, the Astros have struggled, posting a 6.32 ERA with a 1.68 WHIP while allowing opponents to hit .266. The staff has recorded 139 strikeouts but has also issued 80 walks, which has contributed to their difficulties.

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A key theme for Houston is the contrast between offense and pitching. While their .270 batting average and 85 runs scored show a strong ability to generate offense, the 6.32 ERA and 1.68 WHIP highlight significant challenges on the mound, which have made it difficult to convert offensive production into wins.

Mariners Looking to Build on Home Success

Seattle comes into this matchup with a 5-9 overall record and a 4-4 record at home. The Mariners have gone 1-4 over their last five games, although they did pick up a recent win over Houston. Before that victory, they dropped several games to Texas and also lost a close extra-inning contest against Los Angeles, showing that they have also faced inconsistency.

Offensively, Seattle is hitting .190 with 49 runs scored and 87 hits, along with 12 home runs. Their on-base percentage is .297, and their slugging percentage is .311. On the pitching side, the Mariners have been strong, posting a 2.86 ERA with a 0.98 WHIP while holding opponents to a .212 batting average. They have recorded 125 strikeouts and issued just 30 walks, reflecting a disciplined and effective pitching staff.

The biggest strength for Seattle is clearly its pitching. With a team ERA of 2.86 and a WHIP below 1.00, the Mariners have consistently limited opposing offenses. That ability has helped keep them competitive even when their own offensive production has been limited.

Houston Astros vs Seattle Mariners Picks and Prediction

Houston Astros vs Seattle Mariners Pick

Pick: Mariners Moneyline

Seattle stands out in this matchup due to its pitching advantage and Houston’s recent struggles. The Mariners have a 2.86 ERA compared to Houston’s 6.32, which is a significant gap in run prevention. Additionally, Seattle just picked up a win over Houston, while the Astros have lost five straight games. Even though Houston’s offense has been strong, the Mariners’ pitching consistency gives them the edge in this contest.

Houston Astros vs Seattle Mariners Total Pick

Take the over if set at 7.5

With no total provided, I would wait to see the number before making a final call. Houston’s offense has been productive with 85 runs scored and a .270 batting average, while Seattle has been strong on the mound with a 2.86 ERA and a .212 opponent batting average. This creates a contrasting dynamic where the final total line will be important in determining the best play.

Final Score Prediction: Mariners 5 – Astros 3

This prediction was written before the completion of game play on Saturday.

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