Kansas City Royals vs Athletics Picks & Predictions for Saturday, September 27, 2025

By: Kim Smith Published 09/27/2025, 12:10 AM ET
Use Code PPWC

The Kansas City Royals (79-78, 2nd in AL Central) face the Athletics (71-86, 4th in AL West) in the second game of a three-game series at Sutter Health Park, with the Royals battling to keep their slim AL wild-card hopes alive. All eyes are on Bobby Witt Jr. for Kansas City and Brent Rooker for the Athletics, as their performances could sway this interleague clash. Our free MLB picks spotlight these stars to uncover the best betting opportunities in a game critical for Kansas City’s postseason push.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
Video: Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026

Game Details

  • Date: September 27, 2025
  • Time: 2:05 AM EDT (12:05 AM PDT)
  • Venue: Sutter Health Park, West Sacramento, California
  • Broadcast Info: MLB Network (national), Bally Sports Kansas City (Royals broadcast), NBC Sports California (Athletics broadcast)
  • Weather: 68Β°F, clear skies, 5-8 mph winds blowing out to left fieldβ€”slightly favoring hitters.

Spotlight Player(s)

  • Kansas City Royals: Bobby Witt Jr. (SS): Witt (.295 AVG, 31 HR, 110 RBI) is the Royals’ cornerstone, hitting .340 with 4 HR and 10 RBI over his last 10 games. Against the Athletics in 2025, he’s 7-for-15 with 2 HR and 6 RBI, including a homer on 6/13/25. His .506 SLG and 32 stolen bases make him a dual threat against right-handers like J.T. Ginn.
  • Athletics: Brent Rooker (DH): Rooker (.268 AVG, 38 HR, 95 RBI) leads the A’s with a .512 SLG, going 8-for-32 with 3 HR in his last 10 games. He’s 3-for-9 with a homer against the Royals this season, thriving against right-handers like Michael Wacha (.290 AVG). His power at Sutter Health Park is key.
  • Impact: Witt’s speed and hitting prowess could spark the Royals’ offense, while Rooker’s homer potential keeps the A’s competitive in a hitter-friendly park.

Supporting Cast & Depth

  • Royals: Vinnie Pasquantino (.280 AVG, 31 HR, 108 RBI) and Maikel Garcia (.285 AVG, 36 2B) add offensive depth, with Pasquantino’s 6 RBI in the last series (9/23-9/25) proving clutch. The bullpen (3.64 ERA, 41 saves) is solid but fatigued after recent close games, with Lucas Erceg (3.20 ERA) as the closer. Injuries to Cole Ragans (shoulder) and MJ Melendez (wrist) limit options.
  • Athletics: JJ Bleday (.241 AVG, 20 HR) and Shea Langeliers (.225 AVG, 25 HR) provide power, but the lineup struggles (.238 AVG, 27th in MLB). The bullpen (4.10 ERA) is inconsistent, with Mason Miller (2.90 ERA, 28 saves) as the lone bright spot. Injuries to Luis Severino (elbow) and T.J. McFarland (forearm) hurt depth.
  • Edge: Royals’ stronger lineup and bullpen give them an advantage, but the A’s power hitters like Rooker can exploit Kansas City’s pitching weaknesses.

Betting Line Breakdown

  • Moneyline: Royals -130 (57%), Athletics +110 (48%)
  • Run Line: Royals -1.5 (+140, ~42%), Athletics +1.5 (-165, ~62%)
  • Total: Over 8.5 (-110, ~52%), Under 8.5 (-110, ~52%)
  • Player Influence: Witt’s hot bat (.340 in last 10) could drive the Royals to cover or win, while Rooker’s power (.512 SLG) supports the over if he connects early. The Royals’ edge with Wacha and their offense makes them favorites, but the A’s underdog value keeps it close.

Picks For Royals vs Athletics

  1. Bobby Witt Jr. Over 1.5 Hits + Runs + RBI (-105): Witt’s .295 AVG, .360 clip against right-handers, and 7-for-15 mark with 2 HR vs. the A’s this season make this a strong prop. His leadoff role and Sutter Health Park’s hitter-friendly conditions ensure multiple contributions.
  2. Royals Moneyline (-130): Kansas City’s 4-3 record in the 2025 series, Wacha’s 3.01 ERA, and superior offense (.245 AVG, .698 OPS vs. A’s .238 AVG, .690 OPS) favor them. The Athletics’ 4.10 bullpen ERA and 35-43 home record tilt this toward the Royals.
  3. Over 8.5 Total Runs (-110): Sutter Health Park’s hitter-friendly setup, Ginn’s 4.65 ERA, and the Royals’ potent bats (Witt, Pasquantino) suggest runs. Rooker’s power and the A’s .470 SLG at home, combined with 4 of 7 head-to-heads in 2025 clearing 8.5, support the over.
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.