Kansas City Royals vs Philadelphia Phillies Picks and Prediction for Friday September 12 2025

By: Eddie Kline Published 09/12/2025, 12:55 AM ET

Royals Preview

In Friday night MLB interleague action, the Kansas City Royals will battle the Philadelphia Phillies from Citizens Bank Park. Be ready for the baseball season with all of our MLB predictions. The Royals (74-73) are four games below .500 on the road and are 4.5 games back in the race for the final AL Wild Card spot. Last night, Kansas City batters left eight men on base and struck out 11 times during a 3-2 road loss against Cleveland.

Thirty-three year old righty Michael Lorenzen (5-10 4.63 ERA) will take the mound for the Royals in this matchup. In his last start, Lorenzen (5.1 IP) gave up four runs and fanned five batters during a 5-1 home loss versus Minnesota.

Phillies Preview

The Philadelphia Phillies are riding a four-game winning streak and are on the verge of clinching the NL East Division title. Last night, 3B Otto Kemp went 2-for-4 with a home run and three RBIs to power Philadelphia to a 6-4 home victory versus New York. OF Nick Castellanos added a pair of hits and scored twice for the Phillies (87-60), who improved to 49-23 at home.

Thirty-one year old righty Walker Buehler (7-7 5.45 ERA) will make his first start of the year for the Phillies. Buehler, who was released by the Red Sox, sports and ugly 1.56 WHIP across 112 plus innings.

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Phillies vs Royals Pick

Philadelphia 3B Alec Bohm (shoulder) is currently on the 10-day injured list and will miss this series. Through 147 games, Kansas City ranks 24th in OPS and 28th in runs scored. For the season, Philadelphia ranks 4th in OPS and 9th in runs scored. Take the Royals to win on the road. Final Score Prediction, Kansas City Royals win 5-3.

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