Los Angeles Angels vs Chicago Cubs Picks and Prediction for Wednesday, April 1, 2026

By: Jake Allman Published 04/01/2026, 12:30 AM ET
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The Los Angeles Angels head to Wrigley Field to face the Chicago Cubs in an afternoon matchup at 2:20 PM ET. Chicago comes in at 2-2 and just picked up a 7-2 win over Los Angeles, while the Angels sit at 2-3 after dropping three straight games. The Cubs are slight home favorites, and both teams bring similar offensive production into this game with identical .229 batting averages. Elevate your MLB game with our top-notch MLB picks.

Angels Preview

Los Angeles has shown power early with 10 home runs and a .434 slugging percentage, but recent results have been rough with losses in three straight. Mike Trout has been the clear leader, hitting .353 with two home runs and a .706 slugging percentage. The lineup has produced 27 runs in five games, though bullpen issues have shown up with a 4.29 ERA and a 1.67 WHIP. Injuries in the pitching staff, including multiple arms on the IL, continue to impact depth.

Yusei Kikuchi gets the start for Los Angeles after allowing two earned runs over 4.1 innings in his first outing. He gave up eight hits with a 2.08 WHIP, showing that traffic on the bases has been a concern. Kikuchi has limited walks, but contact against him has been consistent. Against a Cubs lineup that just scored seven runs, he will need better command to keep this game under control.

Cubs Preview

Chicago comes off a strong bounce-back win and has shown some offensive consistency with 24 runs scored through four games. Ian Happ leads the team with three home runs and five RBIs, while Pete Crow-Armstrong is hitting .313. The Cubs' pitching staff has a lower WHIP at 1.14 and has limited walks effectively. Even with Seiya Suzuki out, the lineup has still produced enough to stay competitive.

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Matthew Boyd takes the mound for Chicago after a tough first start, where he allowed six earned runs in 3.2 innings. His 14.73 ERA stands out, but he also recorded seven strikeouts, showing he still has swing-and-miss ability. The issue has been hard contact, including a home run allowed. If Boyd can settle in and limit damage early, Chicago has the bullpen advantage behind him.

Cubs vs Diamondbacks Pick

The matchup points toward offense, with both starters showing vulnerability in their first outing. Los Angeles brings more power, but Chicago has already handled Kikuchi once and carries better bullpen numbers into this game. The Cubs also have momentum after the 7-2 win in this series.

Prediction: Cubs 6, Angels 5

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