Los Angeles Angels vs Milwaukee Brewers Picks and Predictions for Tuesday, September 16, 2025

By: David Anicetti Published 09/16/2025, 12:35 AM ET
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The Los Angeles Angels visit the Milwaukee Brewers at American Family Field on Tuesday at 7:40 p.m. ET on MLB.TV. Milwaukee enters at 91-59 with a strong 48-27 home record, while Los Angeles sits at 69-81 and 32-43 away. The Angels lost 11-2 to Seattle on Sunday, while the Brewers lost to St. Louis 3-2. Get on base with our MLB Free Picks.

Los Angeles Angels Preview

The Angels have struggled to generate consistent offense, batting just .228 as a team with 639 runs scored this season. Taylor Ward has been a run producer with 31 home runs and 98 RBI, while Jo Adell leads the team with 36 homers. Injuries have impacted the lineup, including Nolan Schanuel and Zach Neto, but Neto still leads the team with 129 hits. Mike Trout’s .361 on-base percentage has provided run-scoring opportunities for the Angels.

Caden Dana takes the mound with just 15.2 big league innings under his belt. He has a 6.32 ERA with 19 strikeouts but has struggled with command, issuing 11 walks. Against a disciplined Brewers lineup, control issues could be a major problem. The Angels’ pitching staff carries a 4.83 ERA and 1.44 WHIP, numbers that have made it difficult to stay competitive against stronger and more disciplined lineups.

Milwaukee Brewers Preview

Milwaukee has been one of the more balanced teams in baseball, hitting .260 as a group and ranking near the top of the league with 762 runs scored. Christian Yelich remains the centerpiece, driving in 96 runs with 28 home runs, while Sal Frelick’s .295 average and .359 on-base percentage have kept the bases filled. Brice Turang has added 156 hits and 91 runs scored, giving the Brewers multiple ways to produce.

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Freddy Peralta is set to start and has been excellent all season, posting a 16-6 record with a 2.69 ERA and 185 strikeouts across 163.2 innings. His ability to limit hits, just 115 allowed, has been a difference-maker. With Milwaukee’s bullpen and overall staff carrying a 3.63 ERA and 1.24 WHIP, the Brewers have been difficult to beat at home.

Los Angeles vs Milwaukee Prediction

Milwaukee holds the advantage at the plate and on the mound with starting pitcher Freddy Peralta. Peralta’s consistency and the Brewers’ balanced offense make them a strong favorite, especially against an Angels team that struggles to reach base and prevent runs. Expect the Brewers to control the game at home. Final Score Prediction: Milwaukee Brewers win 8-2.

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