Los Angeles Dodgers vs Arizona Diamondbacks Pick and Prediction for Thursday September 25, 2025

By: Cameron Ross Published 09/25/2025, 12:15 AM ET
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Dodgers vs Diamondbacks Game Information

The Los Angeles Dodgers stayed on the road Thursday night for game three of three in Arizona against the Arizona Diamondbacks at Chase Field at 3:40 PM. Los Angeles is a playoff team with 88 wins on the year, looking to sew up the division title in the final week of the season. Arizona comes into this matchup 3 games above .500 in pursuit of a playoff spot, riding a lengthy winning streak. Stay in the action with our free MLB Picks.

Dodgers Preview

Offensively, Los Angeles has been top tier this season with nearly 800 runs on 1341 hits. The Los Angeles power has carried the team with a .440 team slugging percentage and 234 total home runs. The Los Angeles pitching has been mediocre this season, with a 4.03 team ERA. Freddie Freeman is at the top of the batting order in the Los Angeles offense with a .292 batting average. Shohei Ohtani is the power for Los Angeles, leading the team with 53 home runs and 99 RBIs on the year.

Diamondbacks Preview

The Arizona pitching has been mediocre this season, with a 4.43 team ERA, but the team has allowed only nine total runs over its last three victories. The Arizona offense has been stout this season, boasting a .252 batting average, as the Diamondbacks have scored 778 runs on 1339 total hits. Geraldo Perdomo has done a ton for Arizona this season, leading the team with a .291 batting average and 98 total RBI's.

Dodgers vs Diamondbacks Pitching Matchup

Yoshinobu Yamamoto will take the mound Thursday for Los Angeles with eleven wins and eight losses on the year, 2.58 ERA across 167.2 innings of work. Zac Gallen will counter for Arizona with 13 wins and 14 losses and a 4.70 ERA in just under 188 total innings of work.

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Dodgers vs Diamondbacks Pick

Both teams have a ton to play for, but the Dodgers are in the better spot in this game. LA is trying to sew up the division, while the Diamondbacks are trying to get into October. Look for the Dodgers to back their pitcher Thursday night on the road, leading to the win as they inch closer to a division title.

Pick: Los Angeles Dodgers -154

Secondary: Β Over 8.5

Lean: Shohei Ohtani Over 1.5 Bases

Final Score Prediction:Β  Los Angeles Dodgers win 6-4

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