Los Angeles Dodgers vs Baltimore Orioles Picks and Predictions for Saturday, September 6, 2025

By: David Anicetti Published 09/06/2025, 12:25 AM ET
Use Code PPWC

The Los Angeles Dodgers visit the Baltimore Orioles on Saturday at Camden Yards for the second game of a three-game series, with the first pitch set for 5:05 PM ET. Los Angeles enters at 78-62, leading the NL West by just two games, and has three straight losses. Baltimore sits at 64-76 and out of the race, but the Orioles have won four of the last five, including a series win in San Diego. With Yoshinobu Yamamoto facing Trevor Rogers, bettors should look at our MLB picks.

Los Angeles Dodgers Preview

Los Angeles turns to Yoshinobu Yamamoto, who has been one of the most reliable arms in their rotation. He has a record of 11–8 with a 2.82 ERA, 1.05 WHIP, and 167 strikeouts in 146.2 innings. He has limited homers to 13 and consistently works deep into games. The Dodgers’ offense is powered by Shohei Ohtani, who has launched 46 home runs with 87 RBI and a .279 average. Freddie Freeman has a team-best .294 batting average and 139 hits, while Mookie Betts continues to contribute with 15 homers and 61 RBI.

Despite that talent, Los Angeles has slumped recently. They have dropped five of the last seven, scoring just 10 total runs in the Pittsburgh series. As a team, they are batting .252 with 205 home runs, but the timing of hits has been an issue. The pitching staff has a 4.13 ERA and 1.29 WHIP.

Baltimore Orioles Preview

Baltimore counters with Rogers, who has been lights-out this season. The left-hander is 8-2 with a 1.39 ERA and 0.82 WHIP through 90.1 innings. He has struck out 81 while allowing just three home runs, while playing for a team that gives him little run support. Gunnar Henderson leads with a .278 average, 16 homers, and 61 RBI. Colton Cowser and Adley Rutschman have provided key hits, but the overall production is average, with the team sitting at .242 with 170 home runs.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

 Orioles vs Dodgers Prediction

This matchup sets up as a duel between a solid Dodgers lineup and one of the hottest pitchers in baseball. Los Angeles will test Rogers’ ability, while Baltimore needs Henderson and the supporting bats to capitalize on Yamamoto’s occasional command lapses.

Final Score Prediction: Dodgers 4, Orioles 2

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Min. Deposit $5
Wagering 1x Deposit
Cashable No
DraftKings Sport

New DraftKings Customers: Bet $5+ Get $100 in Bonus Bets Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: NBA Finals Game 5 Picks & Predictions 🔥 Knicks vs Spurs | Steve Seagrave
NBA Finals Game 5 Picks & Predictions Knicks vs Spurs | Steve Seagrave
Video: MLB Picks Today ⚾ Guardians-Tigers, Rays-Angels & Phillies-Brewers | David Delano
MLB Picks Today Guardians-Tigers, Rays-Angels & Phillies-Brewers | David Delano

Orioles vs Dodgers Best Picks:

  • Under 8 runs - both starters limit opposing lineups' run chances.
  • Dodgers moneyline - the Dodgers have struggled but Baltimore traded away its best power hitters at the deadline.

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.