Los Angeles Dodgers vs Philadelphia Phillies Picks, Prediction, Odds, and Line Movement for Wednesday July 22 2026

By: Kyle Kargel Published 07/22/2026, 08:48 AM ET
Dodgers vs Phillies prediction

The Los Angeles Dodgers vs Philadelphia Phillies series finale Wednesday features Eric Lauer opposing Aaron Nola, with the series tied heading into the rubber match. Bettors searching for more MLB picks will want to track how the moneyline and total have shifted throughout the series, since both markets have moved leading into first pitch.

TLDR: Quick Picks and Prediction

  • Moneyline Pick: Los Angeles Dodgers -120
  • Total Pick: Over 9.5 (-107)
  • Final Score Prediction: Dodgers 6, Phillies 5

Odds and Line Movement

Current Odds

Team Moneyline Run Line Total
Los Angeles Dodgers -120 -1.5 (+129) Over 9.5 (-107)
Philadelphia Phillies +100 +1.5 (-156) Under 9.5 (-113)

Line Movement - Moneyline

Date Time LA Dodgers Philadelphia Public ($, #)
07/22 05:57:25AM -120 +100 LAD 94%, 84%
07/22 02:49:17AM -120 +100 LAD 92%, 83%
07/22 00:24:08AM -120 +100 LAD 95%, 81%
07/21 08:54:26PM -120 +100
07/21 07:45:11PM -118 -102
07/21 07:45:11PM -118 -102
07/21 03:36:16PM -110 -110
07/21 03:36:16PM -110 -110

Line Movement - Total

Date Time Over Under
07/21 08:56:17PM 9.5o -107 9.5u -113
07/21 08:54:26PM 9.5o -111 9.5u -109
07/21 07:45:11PM 10o -110 10u -110
07/21 05:54:16PM 10o -108 10u -112
07/21 03:36:16PM 10o -110 10u -110

Dodgers vs Phillies: Key Matchups and Game Preview

Wednesday's finale pits Eric Lauer against Aaron Nola after the teams split the first two matchups of the series. Lauer is 4-5 with a 4.81 ERA and 1.28 WHIP through 76.2 innings, allowing 71 hits, 27 walks and 18 home runs while recording 47 strikeouts. His low strikeout rate and elevated home-run total create risk against a Philadelphia lineup that has hit 133 homers, including 33 from Kyle Schwarber.

Nola Continues to Struggle

Nola has struggled even more, going 3-7 with a 5.68 ERA and 1.45 WHIP across 103 innings. He has surrendered 114 hits, 35 walks and 23 home runs despite striking out 108 batters, and that home-run vulnerability is concerning against a Dodgers offense batting .260 with a .341 on-base percentage and .430 slugging percentage.

Ohtani Leads Los Angeles' Attack

Shohei Ohtani leads Los Angeles with a .287 average, .394 on-base percentage, .531 slugging percentage and 22 homers, while Andy Pages has supplied a team-high 68 RBI. The Dodgers hold clear overall advantages in run production, pitching and recent road performance, scoring 526 runs while posting a 3.53 team ERA and 1.14 WHIP.

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Schwarber and Philadelphia's Power

Philadelphia's offense has been less consistent, batting .236 with a .303 on-base percentage and .402 slugging mark, but Schwarber's power and Brandon Marsh's .290 average give the Phillies multiple ways to pressure Lauer. Philadelphia has scored 443 runs with a 4.22 ERA and 1.31 WHIP.

Line movement shows the Dodgers' moneyline settling at -120 after moving from a pick'em number earlier in the series, with public backing on Los Angeles consistently heavy, ranging from 92% to 95% across recent timestamps. The total has come down from 10 to the current 9.5, with the over now priced at -107 after being nearly even at several points earlier in the series.

LAD vs PHI Key Injuries and Things To Know

The injury picture also favors Los Angeles slightly, although its bullpen is missing Edwin Diaz, Blake Treinen and Ben Casparius, which could matter if Lauer exits early. Enrique Hernandez is also unavailable. Philadelphia is without catcher Garrett Stubbs and several relievers, including Lou Trivino, Tanner Banks and Brad Keller, leaving its bullpen thinner behind a starter who has frequently allowed traffic. Johan Rojas is also sidelined, reducing the Phillies' outfield depth and defensive flexibility.

Dodgers vs Phillies Side and Over/Under Picks

  • Moneyline Pick: Los Angeles Dodgers -120
  • Total Pick: Over 9.5 (-107)

With both starters allowing home runs at a high rate and each bullpen missing important pieces, this matchup is positioned for more offense than Tuesday's 2-1 result. The Dodgers' deeper lineup and superior overall pitching profile provide the stronger edge on the moneyline.

Final Score Prediction

Final score prediction for this series finale:

  • Los Angeles Dodgers: 6
  • Philadelphia Phillies: 5

How to Wager On Dodgers vs Phillies

Bettors looking to build out this Dodgers vs Phillies card have several tools available beyond the standard side, total and moneyline markets. Comparing Lauer's and Nola's shared home-run vulnerability is a strong angle for first-five-innings and pitcher prop markets, while the total's drop from 10 to 9.5 suggests shopping multiple books before locking in a number. For those wanting an extra layer of analysis, the AI picks tool can help cross-reference projections, and reviews like the Dimers review and the Oddible review break down how each platform grades matchups like Phillies vs Dodgers before first pitch.

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