Los Angeles Dodgers vs San Francisco Giants Picks and Predictions for Thursday April 23 2026

By: Kim Smith Published 04/23/2026, 12:45 AM ET
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The Los Angeles Dodgers head to Oracle Park in San Francisco, California to face the San Francisco Giants on Thursday, April 23, 2026, with first pitch scheduled for 3:45 PM and coverage available on MLB.TV. At the time of this writing the odds were not released. This divisional matchup features a Dodgers team that has been productive on the road against a Giants team looking to build consistency at home. Be sure to check out free MLB picks for additional daily analysis.

Starting Pitchers Matchup

Tyler Glasnow will take the mound for Los Angeles, entering with a 2-0 record, a 3.24 ERA, and a 0.84 WHIP across 25.0 innings. He has allowed just 15 hits while striking out 29 batters and issuing six walks, showing strong control and efficiency. On the other side, Logan Webb gets the start for San Francisco, holding a 2-2 record with a 5.40 ERA and a 1.40 WHIP over 30.0 innings. He has given up 31 hits while recording 27 strikeouts and 11 walks, indicating more traffic on the bases compared to his counterpart.

Dodgers Showing Strength Away From Home

Los Angeles enters this matchup with a 16-7 overall record and a 7-4 mark on the road. Over their last five games, the Dodgers have recently lost to San Francisco but also secured wins over Colorado and Colorado again, while dropping two contests to Colorado as well. That stretch shows a team that has been competitive but has experienced some inconsistency in recent outings.

From a statistical standpoint, Los Angeles has been highly productive, posting a .286 batting average with 134 runs and 225 hits. Their power numbers stand out with 42 home runs, supported by a .362 on-base percentage and a .494 slugging percentage. On the pitching side, the Dodgers have recorded a 3.41 ERA and a 1.12 WHIP, while limiting opponents to a .211 batting average.

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A key strength for Los Angeles is their offensive production, as their .286 batting average combined with a .494 slugging percentage highlights their ability to consistently generate runs and apply pressure throughout the lineup.

Giants Looking to Hold Serve at Oracle Park

San Francisco comes into this game with a 10-13 overall record and a 4-7 mark at home. In their last five games, the Giants have recently won over Los Angeles and also picked up victories against Washington multiple times, while suffering a loss to Washington as well. That recent stretch reflects a team that has shown flashes of strong play but has yet to establish full consistency.

Looking at the numbers, San Francisco has posted a .250 batting average with 78 runs and 196 hits. Their offense has produced 13 home runs while maintaining a .293 on-base percentage and a .360 slugging percentage. On the pitching side, the Giants hold a 4.01 ERA and a 1.31 WHIP, while allowing opponents to hit .232.

A notable weakness for San Francisco is their limited power production, as their 13 home runs and .360 slugging percentage indicate fewer extra-base opportunities compared to their opponent. That could be a factor in a matchup against a more productive offense.

Los Angeles Dodgers vs San Francisco Giants Picks and Prediction

Los Angeles Dodgers vs San Francisco Giants Pick

Pick: Los Angeles Dodgers Moneyline

Los Angeles enters this matchup with a clear advantage in offensive production and pitching efficiency. Their higher batting average, on-base percentage, and slugging percentage highlight a more consistent ability to generate runs, while their lower ERA and WHIP show stronger control on the mound. Although San Francisco secured a recent win in this matchup, the overall statistical profile favors Los Angeles. With a more balanced approach and greater offensive output, the Dodgers are in a strong position to take this game.

Los Angeles Dodgers vs San Francisco Giants Total Pick

Pick: Over 8.5

Both teams have shown the ability to contribute offensively, and the pitching numbers suggest opportunities for scoring. While Los Angeles has been more effective on the mound overall, San Francisco’s pitching metrics indicate that runs could be available. I expect both teams to generate scoring chances, especially with Los Angeles’ strong offensive production, making the over a solid play in this matchup.

Final Score Prediction: Los Angeles Dodgers 6 – San Francisco Giants 4

This prediction was written before the completion of game play on Wednesday.

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