Los Angeles Dodgers vs Seattle Mariners Picks & Predictions for Saturday, September 27, 2025

By: Kim Smith Published 09/27/2025, 12:05 AM ET
Seattle Mariners
Use Code PPWC

The Los Angeles Dodgers (90-67, 1st in NL West) and Seattle Mariners (90-67, 1st in AL West) clash in the second game of a three-game interleague showdown at T-Mobile Park, a potential World Series preview that reignites memories of their intense 2024 encounters. With both teams having clinched their divisions, this series is about postseason momentum and bragging rights between two powerhouse franchises led by MVP candidates Shohei Ohtani and Cal Raleigh. Seattle’s recent home dominance and the Dodgers’ star-studded lineup set the stage for a thrilling battle. Our free MLB picks weave the narrative and stats to find the best betting angles.

The Storyline

This Dodgers-Mariners matchup is a clash of titans, pitting two division champions with deep playoff aspirations against each other in a rare late-season interleague duel. Seattle, riding a franchise-record 16-1 stretch at T-Mobile Park, seeks to assert their AL supremacy and avenge a 6-4 loss to the Dodgers in spring training (3/7/25). The Dodgers, fresh off their 2024 World Series run, aim to flex their offensive muscle and prove they can handle Seattle’s elite pitching in a pitcher-friendly park. With Ohtani chasing a 55-homer season and Raleigh already at 59, this game is a showcase of star power and a test of which team can impose its style—LA’s relentless offense or Seattle’s suffocating pitching.

Matchup Breakdown

  • Team Strengths/Weaknesses: The Dodgers boast a top-3 offense (.254 AVG, .750 OPS, 760 runs), led by Ohtani (.290 AVG, 54 HR) and Mookie Betts (.260 AVG, 19 HR), but their bullpen (3.80 ERA) is patchwork due to injuries (Evan Phillips, forearm). Seattle’s strength lies in their pitching (3.89 ERA, 1.22 WHIP), with a deep rotation and bullpen (3.40 ERA, 40 saves). Their offense (.244 AVG, .740 OPS) relies on Raleigh and Julio RodrĂ­guez (.269 AVG, 27 HR), but struggles against elite right-handers.
  • Key Positional Battles: Ohtani and Freddie Freeman (.295 AVG) face Seattle’s Logan Gilbert, who’s 2-0 with a 2.45 ERA against LA in 2025. Seattle’s RodrĂ­guez and Raleigh test LA’s Emmet Sheehan, who’s 1-0 with a 2.86 ERA vs. the Mariners. The Dodgers’ deeper lineup gives them an edge, but Seattle’s bullpen could dominate late.

Odds & Public Perception

  • Opening Line vs. Current Line: Opened at Dodgers -125, Mariners +105; now Dodgers -120 (55%), Mariners +100 (50%). Run line: Dodgers -1.5 (+140, ~42%), Mariners +1.5 (-165, ~62%). Total: Over 7.5 (-110, ~52%), Under 7.5 (-110, ~52%).
  • Public vs. Sharp Money: Public betting favors the Dodgers (60% of ML handle), drawn by Ohtani and LA’s 38-40 road record. Sharp money leans toward the Mariners’ +1.5 and under, citing T-Mobile’s pitcher-friendly dimensions and Seattle’s 51-27 home mark.

Betting Strategy

This is a low-scoring, pitcher-driven game, with T-Mobile Park’s deep fences and Seattle’s elite pitching favoring the under. The Dodgers’ -120 ML offers value, but the steep price reflects their star power rather than a clear edge. Seattle’s +1.5 run line is a sharp play, given their home dominance and ability to keep games close against top teams. Live betting could be key—watch for early scoring chances against Sheehan, as Seattle’s bullpen (3.40 ERA) often shuts down late rallies.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No
Video: World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
World Cup: Mexico vs England BEST Bets & Predictions | July 5, 2026
Video: Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026
Brazil vs Norway: The Bet You AREN'T Thinking Of! | BEST World Cup Predictions | July 5, 2026

Picks For Dodgers vs Mariners

  1. Mariners +1.5 (-165): Seattle’s 51-27 home record, Gilbert’s 3.53 ERA, and 16-1 recent home stretch make them a strong bet to keep this within a run. The Dodgers’ bullpen vulnerabilities (3.80 ERA) and Seattle’s 7-3 record vs. winning teams at home since August support this pick.
  2. Under 7.5 Total Runs (-110): T-Mobile’s pitcher-friendly setup, Gilbert’s 1.20 WHIP, and Sheehan’s 2.86 ERA suggest a low-scoring affair. Both teams’ disciplined approaches (Dodgers 7.8 K/game, Mariners 7.9) and 3 of 5 interleague games in 2025 staying under 8 runs back this choice.
  3. Cal Raleigh Over 1.5 Hits + Runs + RBI (-115): Raleigh’s 59 HR and .350 AVG vs. right-handers like Sheehan make this a prime prop. His 3-for-8 with 2 HR against LA this season and hot September (.320 AVG) ensure he’ll contribute in multiple ways.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.