Miami Marlins vs San Diego Padres Picks and Predictions for Sunday, September 20th, 2026

By: Cameron Ross Published 09/20/2026, 01:10 AM ET

Miami Marlins vs San Diego Padres Game Information

The Miami Marlins continue their West Coast road trip Sunday afternoon with a 4:10 PM matchup in San Diego. Miami is hovering around .500 thus far this year, coming into Sunday in the middle of the National League East. The San Diego Padres are well above. 500 coming into Sunday, competing for a National League wild card spot. Stay in the loop with our MLB Picks.

Miami Marlins Preview

Eury Perez got the start for Miami on Saturday, allowing 5 runs on 8 hits over 4.2 innings. The Marlins bullpen gave up 2 runs, only 1 earned, on 3 hits through the final 4.2 innings. Josh Ekness took the loss after surrendering the winning run in the bottom of the 10th inning. Jakob Marsee led the Miami offense with 3 hits and 2 runs scored. Otto Lopez added a 2-run home run, while Agustin Ramirez recorded 2 hits, 1 RBI, and 1 run. Griffin Conine tied the game with a solo home run in the 9th inning.

San Diego Padres Preview

Casey Mize started for San Diego on Saturday, giving up 5 runs on 5 hits and 5 walks through 3 innings. The Padres bullpen was fantastic, allowing just 1 run on 5 hits across the final 7 innings. David Morgan earned the win after pitching a scoreless 10th inning. Ty France led the San Diego offense with 3 hits, 1 RBI, and 1 run scored. Samad Taylor hit a home run and drove in 2 runs, while Fernando Tatis Jr. also hit a home run. Ethan Salas delivered the game-winning RBI single in the bottom of the 10th inning.

Miami Marlins vs San Diego Padres Pitching Matchup

Sandy Alcantara will take the mound for Miami. Alcantara is 13-10 with a 3.84 ERA and a 1.23 WHIP across 206 innings. He has struck out 149 while allowing 195 hits, 58 walks, and 23 home runs. Walker Buehler will start for San Diego. Buehler enters at 8-6 with a 4.58 ERA and a 1.37 WHIP through 143.1 innings, recording 122 strikeouts while surrendering 142 hits, 54 walks, and 20 home runs.

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Miami Marlins vs San Diego Padres Pick

San Diego is the better team overall, but Miami possesses the starting-pitching advantage with Alcantara on the mound. The Marlins right-hander has worked more than 200 innings and has been considerably more reliable than Buehler. San Diego should generate some opportunities at home, but Buehler’s elevated ERA and WHIP leave him vulnerable against Miami. Take the Marlins to remain competitive throughout and pull off the road upset behind Alcantara.

  • Pick: Miami Marlins
  • Secondary: Under
  • Lean:

Final Score Prediction: Miami Marlins win 4-3

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