Milwaukee Brewers vs Chicago Cubs Picks and Prediction for Tuesday May 19 2026

By: Kim Smith Published 05/19/2026, 12:25 AM ET
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The Milwaukee Brewers and Chicago Cubs meet Tuesday, May 19, 2026, at Wrigley Field in Chicago, Illinois. First pitch is scheduled for 7:40 PM ET with television coverage on MLB.TV. Chicago enters the matchup with a slight edge according to the matchup predictor, while both teams arrive with strong overall records and playoff-caliber starts to the season. The Cubs have been excellent at home this year, while Milwaukee has remained one of the more balanced teams in the division entering this important matchup. At the time of this writing the odds were not released. Be sure to check out our free MLB picks

Strong Pitching Matchup Headlines Tuesday Night

Milwaukee is expected to start Jacob Misiorowski, who enters the game with a 3-2 record, 2.12 ERA, and 0.90 WHIP across 51 innings. He has allowed only 29 hits while striking out 80 batters and giving up four home runs. Chicago will counter with Ben Brown, who has posted a 1-1 record, 1.60 ERA, and 0.86 WHIP through 33.2 innings. Brown has allowed just 19 hits while striking out 34 batters and surrendering only one home run this season.

Brewers Continue Competing in Tight Games

Milwaukee enters Tuesday with a 26-18 overall record and an 11-9 mark on the road. The Brewers have won three of their last five games and recently picked up back-to-back victories over Minnesota after earning a convincing 7-1 win against San Diego. Milwaukee’s recent losses have also been competitive, including a 5-4 defeat against the Twins and a 3-1 loss against the Padres.

The Brewers are batting .244 with 218 runs scored and 30 home runs this season. Milwaukee owns a .333 on-base percentage and .360 slugging percentage while collecting 360 hits overall. The pitching staff has been a major strength, producing a 3.29 ERA and 1.21 WHIP while holding opponents to a .225 batting average.

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One of Milwaukee’s biggest strengths has been run prevention. The Brewers have consistently limited opposing offenses throughout the season, and the staff has done an excellent job avoiding major damage in games. Milwaukee has also remained disciplined offensively with a strong on-base percentage that has helped create scoring opportunities even without overwhelming home run production.

Cubs Relying on Home Field Advantage

Chicago enters this matchup with a 29-18 overall record and a dominant 18-5 record at Wrigley Field. The Cubs have gone 2-3 over their last five games, though they recently earned victories over the White Sox and Atlanta during that stretch. Chicago’s latest two losses both came in higher-scoring games against the White Sox, including a 10-inning defeat.

The Cubs are batting .246 as a team with 241 runs scored and 57 home runs. Chicago owns a .343 on-base percentage and .406 slugging percentage while collecting 394 hits overall. On the mound, the Cubs have produced a 3.99 ERA and 1.20 WHIP while opponents are batting .232 against them.

Chicago’s biggest advantage entering this contest is offensive power combined with home-field success. The Cubs have hit nearly twice as many home runs as Milwaukee and have scored more runs overall. Wrigley Field has also been a major advantage this season, with Chicago winning 18 of its first 23 home games.

Milwaukee Brewers vs Chicago Cubs Picks and Prediction

Milwaukee Brewers vs Chicago Cubs Pick

  • Pick: Chicago Cubs Moneyline

Chicago’s home record has been one of the strongest in baseball entering this matchup, and the Cubs continue to produce offensively at a higher level than Milwaukee. The Cubs have scored 241 runs with 57 home runs while also maintaining a strong .343 on-base percentage. Milwaukee’s pitching numbers are excellent, but Chicago has consistently found ways to win at Wrigley Field. In what projects to be a close game between two quality teams, the Cubs’ offensive edge and home-field success give them the advantage.

Milwaukee Brewers vs Chicago Cubs Total Pick

  • Pick: Under 7.5

I like the under in this matchup because both starting pitchers have been outstanding this season. Jacob Misiorowski enters with a 2.12 ERA and 80 strikeouts, while Ben Brown owns a 1.60 ERA and has allowed only one home run all year. Milwaukee also carries a 3.29 team ERA into the game, and both teams have shown the ability to win lower-scoring contests recently. With two strong pitching staffs and quality starters on the mound, this matchup feels more favorable toward a tighter game.

Final Score Prediction: Chicago Cubs 4 – Milwaukee Brewers 3

This prediction was written before the completion of game play on Monday.

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