Milwaukee Brewers vs Cincinnati Reds Picks and Prediction for Friday September 4 2026

By: Eddie Kline Published 09/04/2026, 12:24 AM ET

Brewers Preview

The Great American Ball Park will play host to a Friday night MLB clash between the Milwaukee Brewers and the Cincinnati Reds. Be ready for the baseball season with all of our MLB predictions. The Brewers (87-54) have won 40 of their 69 road games and own the best overall record in the majors. Last night, a solo shot by 1B Andrew Vaughn was all the offense Milwaukee could muster during a 2-1 road loss against Chicago. SP Logan Henderson (9-3) gave up two runs in seven innings and was the hard luck loser for the Brewers, who hold an eight game lead over the Cubs for the top spot in the NL Central Division.Β Β 

Rookie left-hander Shane Drohan (7-5 3.75 ERA) will make his 17th career major league start for the Brewers. Through 110 plus innings, Drohan has allowed ten home runs and fanned 110 batters while posting a respectable 1.30 WHIP.

Reds Preview

The Cincinnati Reds have won five of their last seven games and are 6.5 games back in the race for the final National League Wild Card spot. On Wednesday, 2B Juan Brito erased an early 3-0 deficit with a three-run blast and Cincinnati went on to capture a 7-3 home victory versus San Diego. OF J.J. Bleday fell a triple short of the cycle and scored twice for the Reds (67-73), who improved to 34-37 at home.Β 

Cincinnati skipper Terry Francona will turn to twenty-four year old righty Rhett Lowder (6-8 5.14 ERA) in the series opener. The Reds have won Lowder’s previous three starts and he has allowed 11 runs (10 ER) across his last 17 plus frames.Β 

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Brewers vs Reds Pick

Cincinnati 1B Spencer Steer is currently sidelined with a wrist injury and will be re-evaluated in a week to see when he can start swinging a bat. Through 141 games, Milwaukee ranks 4th in OPS and 3rd in runs scored. For the season, Cincinnati ranks 23rd in OPS and 24th in runs scored. Take the over. Final Score Prediction, Milwaukee Brewers win 8-5.

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