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Milwaukee Brewers vs. Houston Astros Picks and Prediction for Friday, May 29, 2026

By: Jake Allman Published 05/29/2026, 01:20 AM ET

The Milwaukee Brewers and Houston Astros meet Friday night at Daikin Park, with the first pitch set for 9:10 PM ET on MLB.TV. Milwaukee enters at 33-20 overall and 14-9 on the road, while Houston comes in at 25-32 and 12-14 at home. The Astros are given a slight edge by ESPN Analytics at 54.2%, but Milwaukee brings the better record, stronger pitching, and more stable recent ERA into this matchup. Elevate your MLB game with our top-notch MLB picks.

Brewers Preview

The Brewers have won three straight, beating St. Louis 2-1, 6-0, and 5-1 after dropping two games to the Dodgers. Milwaukee is hitting .246 with a .332 OBP, .364 SLG, and 37 home runs, so the power has not been a major strength. Still, the Brewers have done enough offensively behind William Contreras, who leads the club with a .303 average and 33 RBI, while Jake Bauers has supplied 8 home runs and 30 RBI.

Milwaukee’s bigger edge is on the mound. Coleman Crow gets the start with a 2.61 ERA, 0.77 WHIP, 7 strikeouts, and only 1 walk across 10.1 innings. That is a small sample, but the command has been sharp, and Milwaukee’s team ERA of 3.14 with a 1.19 WHIP gives the Brewers a clear pitching advantage over Houston. The injury list is not empty, with Rob Zastryzny, Gerson Garabito, Quinn Priester, Jared Koenig, and Brandon Woodruff out, but the Brewers have still been holding opponents down.

Astros Preview

Houston has played better over the last five games, winning four of those contests, including a 4-3 win over Texas and a 9-0 shutout in the same series. The Astros’ offense has more pop than Milwaukee’s, with 74 home runs and a .412 slugging percentage. Yordan Alvarez is the main problem for opposing pitchers, posting a .312 average, .422 OBP, .663 SLG, 20 home runs, and 39 RBI, while Christian Walker has added 15 home runs and 40 RBI.

Kai-Wei Teng gives Houston a real chance with a 3-3 record, 2.19 ERA, 1.05 WHIP, 36 strikeouts, and 15 walks across 37 innings. The concern is the full Houston pitching staff behind him, as the Astros own a 5.12 ERA and 1.47 WHIP. Houston also has several injuries, including Josh Hader on the 60-day IL and Lance McCullers Jr. on the 15-day IL, which matters if this game gets tight late.

Astros vs Brewers Pick

The pick is Brewers moneyline, with Milwaukee winning 4-3. Houston has the bigger bats, but Milwaukee has the better overall pitching numbers, the better record, and the cleaner recent ERA. Crow does not need to dominate for seven innings here, but if he keeps the ball in the park and limits free passes, the Brewers can turn this into a bullpen-backed road win. The Astros’ lineup is dangerous enough to avoid a big run-line play, but Milwaukee’s pitching gap makes the Brewers the better side.

Best Picks

  • Brewers moneyline.
  • Lean under if the total is posted at 8.5 or higher.

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Final score prediction: Brewers 4, Astros 3.

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