Milwaukee Brewers vs Minnesota Twins Picks and Prediction for Saturday May 16 2026

By: Kim Smith Published 05/16/2026, 12:30 AM ET
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The Milwaukee Brewers travel to face the Minnesota Twins at Target Field in Minneapolis, Minnesota on Saturday, May 16, 2026, with first pitch scheduled for 7:10 PM ET on MLB.TV. Milwaukee enters the matchup with a 24-17 overall record and a 9-8 mark on the road, while Minnesota comes in at 20-24 overall and 12-11 at home. The matchup predictor favors the Brewers at 58.4% compared to 41.6% for the Twins. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Logan Henderson takes the mound for Milwaukee carrying a 0-1 record with a 4.15 ERA, 0.92 WHIP, 13.0 innings pitched, 10 hits allowed, 16 strikeouts, two walks, and one home run allowed. Minnesota counters with Connor Prielipp, who enters with a 1-1 record, 3.32 ERA, 1.00 WHIP, 19.0 innings pitched, 12 hits allowed, 21 strikeouts, seven walks, and three home runs allowed. Both starters have posted solid WHIP numbers, while Minnesota holds a slight edge in ERA entering the matchup.

Milwaukee Bringing Strong Form Into Minnesota

The Brewers enter this game with a 24-17 overall record and a winning 9-8 mark away from home. Milwaukee has won four of its last five games, recently defeating San Diego twice and New York twice while recently losing once to San Diego. The Brewers have consistently found ways to win close games during this stretch, including back-to-back 4-3 victories over New York and a 7-1 win in their most recent contest.

Milwaukee is batting .245 with 209 runs, 336 hits, 27 home runs, a .336 on-base percentage, and a .359 slugging percentage. On the pitching side, the Brewers have been one of the stronger teams statistically with a 3.35 ERA, 1.23 WHIP, 402 strikeouts, and a .225 opponent batting average. Milwaukee enters with an 11-12 record in night games this season.

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The biggest strength for Milwaukee has been pitching consistency. The Brewers own the better ERA and lower opponent batting average in this matchup, and their staff has generated 402 strikeouts this season. Combined with recent winning form, Milwaukee enters with a strong overall profile despite not relying heavily on home run production.

Minnesota Hoping to Continue Recent Momentum

The Twins enter the matchup at 20-24 overall with a 12-11 home record. Minnesota has also won four of its last five games, recently defeating Miami twice and Cleveland twice while recently losing once to Miami. The Twins are coming off a dominant 9-1 victory and have held opponents to four runs or fewer in four of their last five games.

Minnesota is batting .236 with 211 runs, 347 hits, 49 home runs, a .325 on-base percentage, and a .385 slugging percentage. The Twins pitching staff owns a 4.49 ERA and 1.36 WHIP while allowing opponents to bat .247 against them. Minnesota has also recorded 332 strikeouts while posting an 11-12 record in night games this year.

One major advantage for Minnesota is power production. The Twins have hit 49 home runs this season compared to only 27 for Milwaukee, and they have generated slightly more runs overall despite a lower batting average. If Minnesota can continue recent offensive production, the Twins have the ability to pressure opposing pitching staffs.

Milwaukee Brewers vs Minnesota Twins Picks and Prediction

Milwaukee Brewers vs Minnesota Twins Pick

  • Pick: Milwaukee Brewers Moneyline

Milwaukee enters this game with the stronger overall pitching profile and slightly better recent consistency. The Brewers have won four of their last five games and own a team ERA of 3.35 compared to Minnesota’s 4.49 ERA. Milwaukee also holds the edge in WHIP, strikeouts, and opponent batting average. Even though the Twins have been playing better recently, the Brewers look more balanced entering this matchup.

Milwaukee Brewers vs Minnesota Twins Total Pick

  • Pick: Under 8.5

Take the under if the total is set at 8.5. Milwaukee has relied heavily on pitching throughout the season, entering with a 3.35 ERA and a .225 opponent batting average. The Brewers have also played several close, controlled games recently, including multiple 4-3 results. Minnesota has improved offensively lately, but both starting pitchers enter with solid WHIP numbers and good strikeout production, which should help limit scoring opportunities.

Final Score Prediction: Milwaukee Brewers 4 – Minnesota Twins 3

This prediction was written before the completion of game play on Friday.

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