Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction for Monday May 4 2026
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The Milwaukee Brewers and St. Louis Cardinals meet at Busch Stadium in St. Louis, Missouri, on Monday, May 4, 2026, at 7:45 PM ET, with coverage on MLB.TV/FS1. At the time of this writing the odds were not released. This divisional matchup features two teams with winning records and recent strong performances, and readers can also check out free MLB picks.
Brewers vs Cardinals Starting Pitchers
Milwaukee is expected to start Brandon Sproat, who comes in with an 0-2 record, a 6.75 ERA, a 1.61 WHIP, 26.2 innings pitched, 28 hits allowed, 25 strikeouts, 15 walks, and seven home runs allowed. St. Louis is expected to counter with Kyle Leahy, who enters with a 3-3 record, a 5.52 ERA, a 1.67 WHIP, 29.1 innings pitched, 38 hits allowed, 22 strikeouts, 11 walks, and six home runs allowed. 
Milwaukee Riding Momentum Into Division Clash
The Brewers enter this game with an 18-14 overall record and an 8-6 mark on the road. Milwaukee has been playing well recently, having recently won over Washington by scores of 4-1 and 6-1, and also recently winning over Arizona by scores of 13-1 and 13-2. The Brewers recently lost to Arizona 6-2, giving them four wins in their last five games provided.
Milwaukee is batting .242 as a team with 170 runs, 260 hits, 22 home runs, a .338 on-base percentage, and a .359 slugging percentage. On the pitching side, the Brewers have a 3.56 ERA, a 1.26 WHIP, 117 walks, 300 strikeouts, and a .231 opponent batting average. Milwaukee also has a 10-4 day record in the provided team stats.
The biggest strength for Milwaukee is its pitching efficiency. The Brewers have the lower ERA, lower WHIP, more strikeouts, and lower opponent batting average compared to St. Louis. Even though Milwaukee has fewer home runs, the ability to limit opposing hitters and control innings has been a key factor in its success so far.
St. Louis Building Confidence at Home
The Cardinals come into Monday with a 20-13 overall record and a 9-8 home record. St. Louis has been on an impressive run, recently winning over Los Angeles by scores of 3-2 and 7-2, and also recently winning over Pittsburgh by scores of 10-5, 5-4, and 11-7. That gives the Cardinals five straight wins in the last five games provided.
St. Louis is batting .242 with 165 runs, 268 hits, 44 home runs, a .327 on-base percentage, and a .408 slugging percentage. The Cardinals’ pitching staff has a 4.59 ERA, a 1.42 WHIP, 126 walks, 231 strikeouts, and a .260 opponent batting average. St. Louis also has a 7-7 day record in the supplied team stats.
The key strength for St. Louis is power, as the Cardinals have 44 home runs compared to Milwaukee’s 22. The offensive ability to generate extra-base hits and drive runs gives St. Louis a different profile, though the pitching numbers show higher ERA and WHIP compared to Milwaukee.
Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Bryan Power | +4,192.00 |
| 2 |  Bruce Marshall | +4,189.00 |
| 3 |  Joe Duffy | +2,213.00 |
| 4 |  Sniper Wes | +1,832.00 |
| 5 |  Tom Macrina | +1,044.00 |
Milwaukee Brewers vs St. Louis Cardinals Pick
- Pick: Milwaukee Brewers Moneyline
Milwaukee is the pick because the Brewers hold the advantage in overall pitching metrics and recent performance. The Brewers have won four of their last five games provided and carry the lower ERA, lower WHIP, more strikeouts, and lower opponent batting average. While St. Louis has won five straight and has more home run power, the overall pitching edge for Milwaukee stands out in the provided data.
Milwaukee Brewers vs St. Louis Cardinals Total Pick
- Pick: Take the over if the total is set at 8.5.
I would lean Over 8.5 if that number is available. Both starting pitchers come into this game with ERAs above 5.00, and both teams have shown the ability to score runs recently. Milwaukee has scored 13 runs twice in the last five games provided, while St. Louis has scored 10 and 11 runs in recent wins. With both offenses showing production and both starting pitchers carrying higher ERAs, the data supports a higher-scoring game.
Final Score Prediction: Milwaukee Brewers 6 – St. Louis Cardinals 5
This prediction was written before the completion of game play on Sunday.
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