Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction for Tuesday May 5 2026
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The Milwaukee Brewers will face the St. Louis Cardinals at Busch Stadium in St. Louis, Missouri, on Tuesday, May 5, 2026, with first pitch scheduled for 7:45 PM ET. The game will be available on MLB.TV, and game-time weather is expected to be 56 degrees. At the time of this writing the odds were not released. Be sure to check out free MLB picks for more insights on today’s action.
Starting Pitchers
Brandon Sproat will take the mound for Milwaukee, entering with a 0-2 record, a 6.75 ERA, and a 1.61 WHIP across 26.2 innings pitched. He has allowed 28 hits while striking out 25 batters and issuing 15 walks, along with surrendering seven home runs. Opposing him will be Andre Pallante for St. Louis, who comes in with a 3-2 record, a 3.73 ERA, and a 1.31 WHIP over 31.1 innings. He has allowed 27 hits while striking out 26 batters and issuing 14 walks, while giving up four home runs. 
Milwaukee Continues Road Battle
The Milwaukee Brewers enter this matchup with an 18-15 overall record and an 8-7 mark on the road. In their last five games, they recently lost to Washington in a close 3-2 contest but also recently won over Washington in back-to-back games by scores of 4-1 and 6-1. Prior to that, they recently won over Arizona in a dominant 13-1 result while also recently lost to Arizona in a 6-2 game. This recent stretch reflects a team capable of both strong offensive performances and close, competitive games.
From a statistical standpoint, Milwaukee is batting .239 with 172 runs on 264 hits and 22 home runs. They have posted a .335 on-base percentage and a .354 slugging percentage. On the pitching side, the Brewers hold a 3.56 ERA with a 1.25 WHIP, allowing a .231 opponent batting average. Their staff has issued 118 walks while recording 309 strikeouts, demonstrating solid pitching effectiveness.
A key strength for Milwaukee is their pitching staff, as reflected in their lower ERA, WHIP, and opponent batting average. This ability to limit opposing hitters provides them with a consistent advantage, even when their offensive production fluctuates.
St. Louis Looks to Hold Serve at Home
The St. Louis Cardinals come into this contest with a 20-14 overall record and a 9-9 record at home. In their last five games, they recently lost to Los Angeles in a 4-1 result but also recently won over Los Angeles in back-to-back games by scores of 3-2 and 7-2. Prior to that, they recently won over Pittsburgh in consecutive games by scores of 10-5 and 5-4. This stretch shows a team that has been able to string together wins while remaining competitive.
Offensively, St. Louis is batting .241 with 166 runs on 275 hits and 44 home runs. They have recorded a .325 on-base percentage and a .403 slugging percentage. Their pitching staff carries a 4.54 ERA with a 1.42 WHIP, allowing a .261 opponent batting average. They have issued 130 walks and recorded 236 strikeouts, indicating a mix of production and inconsistency.
One key weakness for St. Louis is their pitching performance, particularly their higher ERA and WHIP compared to Milwaukee. While their offense has shown power with a strong home run total, their ability to consistently limit opposing scoring has been less reliable.
Milwaukee Brewers vs St. Louis Cardinals Picks and Prediction
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Bryan Power | +4,192.00 |
| 2 |  Bruce Marshall | +4,189.00 |
| 3 |  Joe Duffy | +2,213.00 |
| 4 |  Sniper Wes | +1,832.00 |
| 5 |  Tom Macrina | +1,044.00 |
Milwaukee Brewers vs St. Louis Cardinals Pick
- Pick: Milwaukee Brewers Moneyline
The Brewers enter this matchup with a strong advantage in pitching, highlighted by their lower ERA, WHIP, and opponent batting average. While St. Louis has shown offensive power, Milwaukee’s ability to limit runs provides a more stable foundation. Combined with their recent ability to win multiple games, the Brewers are in a good position to come out on top.
Milwaukee Brewers vs St. Louis Cardinals Total Pick
- Pick: Over 8.5
I am leaning toward the over in this matchup due to St. Louis’ offensive production and Milwaukee’s ability to contribute runs. While the Brewers have strong pitching numbers, the Cardinals’ power hitting and Milwaukee’s recent scoring performances suggest this game could produce enough offense to exceed the total.
Final Score Prediction: Milwaukee Brewers 5 – St. Louis Cardinals 4
This prediction was written before the completion of game play on Monday.
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