Minnesota Twins vs Los Angeles Angels Picks and Prediction for Wednesday September 10 2025

By: Eddie Kline Updated 09/10/2025, 12:29 AM ET
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In Wednesday afternoon MLB action, the Minnesota Twins will battle the Los Angeles Angels from Angel Stadium. Be ready for the baseball season with all of our MLB predictions. The Twins (64-81) were major sellers at the trade deadline and will be forced to rebuild in the offseason. Last night, Minnesota 3B Ryan Fitzgerald crushed a two-run bomb in the ninth inning of a 12-2 road loss against Los Angeles.

Twenty-four year old righty Taj Bradley (6-7 4.92 ERA) will take the mound for the Twins in this matchup. Bradley, who was acquired in a trade with Tampa Bay, has surrendered 12 runs across 15 frames in his first three starts for Minnesota.

Angels Preview

The Los Angeles Angels are two games below .500 at home and are on the verge of being eliminated from postseason contention. During last night’s home victory, 3B Yoan Moncada went 2-for-4 with a three-run blast and scored three times to power the Los Angeles offense. Veteran SP Kyle Hendricks (7-9) fanned six batters across seven shutout frames to earn the win for the Angels (68-77).

The Angels will counter with twenty-six year old righty Jose Soriano (10-10 4.07 ERA) in the series finale. Last time out, Soriano was roughed up for eight runs and recorded just seven outs during a 10-4 home loss versus the Athletics.

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Angels vs Twins Pick

Los Angeles C Logan O’Happe has been placed on the 7-day concussion list and will not be eligible to return until September 16th. Through 145 games, Minnesota ranks 17th in OPS and 23rd in runs scored. For the season, Los Angeles ranks 22nd in OPS and 24th in runs scored. Take the Angels to win at home. Final Score Prediction, Los Angeles Angels win 5-3.

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